GENERAL-SYNTHESIS OF PHOSPHATIDYLINOSITOL 3-PHOSPHATES

被引：49

作者：

BRUZIK, KS

KUBIAK, RJ

机构：

[1] Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 14期

关键词：

D O I：

10.1016/0040-4039(95)00317-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Uniform synthetic approach to phosphatidylinositol 3-phosphate, 3,4-bisphosphate and 3,4,5-trisphosphate has been elaborated starting from 1D-1-O-tert-butyldiphenylsilyl- and 1,6-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-myo-inositols using regioselective benzoylation at the 3-, 3,4- and 3,4,5-positions of inositol.

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页码：2415 / 2418

页数：4

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