INFECTIONS COMPLICATING LOW-RISK CESAREAN SECTIONS IN COMMUNITY HOSPITALS - EFFICACY OF ANTIMICROBIAL PROPHYLAXIS

被引：49

作者：

EHRENKRANZ, NJ ^{[1
]}

BLACKWELDER, WC ^{[1
]}

PFAFF, SJ ^{[1
]}

POPPE, D ^{[1
]}

YERG, DE ^{[1
]}

KASLOW, RA ^{[1
]}

机构：

[1] NIAID,BETHESDA,MD 20205

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1990年 / 162卷 / 02期

关键词：

cesarean sections and antibiotic prophylaxis; cesarean sections in community hospitals; endometritis and wound infections after cesarean sections; Prevention of infection after low-risk cesarean sections; risk factors for infection after cesarean sections;

D O I：

10.1016/0002-9378(90)90381-G

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A prospective study of women with low-risk cesarean sections was conducted in four community hospitals to determine the frequency of postoperative infections and identify factors predisposing to endometritis and wound infection. Low-risk cesarean section was defined as a scheduled procedure without an urgent indication, with any duration of ruptured membranes being ≤12 hours. In a cohort of 1863 patients, 26 (1.4%) developed endometritis and 21 (1.1%) had wound infections. Primary cesarean section was associated with endometritis in the cohort (p < 0.01) and in a retrospective study with the same cases as in the cohort (p = 0.01). Absence of antibiotic prophylaxis was associated with endometritis (p ≤ 0.013) or endometritis with wound infection (p < 0.01) in both studies. Without prophylaxis 37 such infections occurred in 957 (3.7%) women; with prophylaxis eight infections occurred in 906 (0.9%) women. Routine timely antibiotic prophylaxis in low-risk cesarean sections could lead to an annual national savings of approximately $9 million. © 1990.

引用

页码：337 / 343

页数：7

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