INDONESIAN MEDICINAL-PLANTS .5. CHEMICAL STRUCTURES OF CALOTROPOSIDES C, D, E, F, AND G, 5 ADDITIONAL NEW OXYPREGNANE-OLIGOGLYCOSIDES FROM THE ROOT OF CALOTROPIS-GIGANTEA (ASCLEPIADACEAE)

被引：38

作者：

SHIBUYA, H ^{[1
]}

ZHANG, RS ^{[1
]}

PARK, JD ^{[1
]}

BAEK, NI ^{[1
]}

TAKEDA, Y ^{[1
]}

YOSHIKAWA, M ^{[1
]}

KITAGAWA, I ^{[1
]}

机构：

[1] OSAKA UNIV, FAC PHARMACEUT SCI, 1-6 YAMADA-OKA, SUITA, OSAKA 565, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1992年 / 40卷 / 10期

关键词：

INDONESIAN MEDICINAL PLANT; CALOTROPIS-GIGANTEA; ASCLEPIADACEAE; OXYPREGNANE-OLIGOGLYCOSIDE; CALOTROPOSIDE; CYMAROSE; OLEANDROSE;

D O I：

10.1248/cpb.40.2647

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Following the chemical characterization of calotroposides A (1) and B (2), five related oxypregnane-oligoglycosides named calotroposides C (3), D (4), E (5), F (6), and G (7) have been additionally isolated from the root of Calotropis gigantea (Asclepiadaceae), an Indonesian medicinal plant. The chemical structures of the new calotroposides have been elucidated on the basis of chemical and physicochemical properties as 12-O-benzoyldeacetylmetaplexigenin 3-O-beta-D-oleandropyranosyl(1 --> 4)-beta-D-oleandropyranosyl(1 --> 4)-beta-D-oleandropyranosyl(1 --> 4)-beta-beta-D-cymaropyranoside for 3, 12-O-benzoyllineolon 3-O-beta-D-oleandropyranosyl(1 --> 4)-beta-D-oleandropyranosyl(1 --> 4)-beta-D-oleandropyranosyl(1 --> 4)-beta-D-cymaropyranosyl(1 --> 4)-beta-D-cymaropyranoside for 4, 12-0-benzoyldeacetylmetaplexigenin 3-O-beta-D-oleandropyranosyl(1 --> 4)-beta-D-oleandropyranosyl(1 --> 4)-beta-D-cymaropyranosyl(1 --> 4)-beta-D-cymaropyranoside for 5, 12-O-benzoyllineolon 3-O-beta-D-oleandropyranosyl(1 --> 4)-beta-D-oleandropyranosyl(1 --> 4)-beta-D-cymaropyrano-syl(1 --> 4)-beta-D-cymaropyranoside for 6, and 12-O-benzoyllineolon 3-O-beta-D-oleandropyranosyl(1 --> 4)-beta-D-cymaropy-ranosyl(1 --> 4)-beta-D-cymaropyranoside for 7.

引用

页码：2647 / 2653

页数：7

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