PEROXIDATION POTENTIAL AND ANTIOXIDANT ACTIVITY OF SERUM IN PATIENTS WITH DIABETES-MELLITUS AND MYOCARD INFARCTION

被引：49

作者：

OZDEMIRLER, G ^{[1
]}

MEHMETCIK, G ^{[1
]}

OZTEZCAN, S ^{[1
]}

TOKER, G ^{[1
]}

SIVAS, A ^{[1
]}

UYSAL, M ^{[1
]}

机构：

[1] ISTANBUL UNIV,FAC MED,DEPT BIOCHEM,ISTANBUL 34390,TURKEY

来源：

HORMONE AND METABOLIC RESEARCH | 1995年 / 27卷 / 04期

关键词：

LIPID PEROXIDATION; ANTIOXIDANT ACTIVITY; SERUM; DIABETES MELLITUS; MYOCARD INFARCTION;

D O I：

10.1055/s-2007-979938

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Endogen malondialdehyde (MDA), diene conjugate levels, the susceptibility to copper-induced lipid peroxidation and antioxidant activity of serum were determined in patients with atherosclerotic diseases such as diabetes mellitus and myocard infarction. Lipid peroxidation susceptibility and antioxidant activity did not change, however, an increase in endogen MDA and diene conjugate levels was observed in serum of these patients, These results indicate the presence of oxidative stress in diabetes mellitus and myocard infarction.

引用

页码：194 / 196

页数：3

共 18 条

[1]

ARSHAD MAQ, 1991, CLIN CHEM, V37, P1756

[2]

Buege J A, 1978, Methods Enzymol, V52, P302

[3] INVITRO LIPID-PEROXIDATION OF HUMAN SERUM CATALYZED BY CUPRIC ION - ANTIOXIDANT RATHER THAN PROOXIDANT ROLE OF ASCORBATE [J].

DASGUPTA, A ;

ZDUNEK, T .

LIFE SCIENCES, 1992, 50 (12) :875-882

[4] ANTIOXIDANT DEFENSES AND LIPID-PEROXIDATION IN HUMAN-BLOOD PLASMA [J].

FREI, B ;

STOCKER, R ;

AMES, BN .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (24) :9748-9752

[5] PLASMA MALONDIALDEHYDE IN TYPE-1 AND TYPE-2 DIABETIC-PATIENTS [J].

GALLOU, G ;

RUELLAND, A ;

LEGRAS, B ;

MAUGENDRE, D ;

ALLANNIC, H ;

CLOAREC, L .

CLINICA CHIMICA ACTA, 1993, 214 (02) :227-234

[6] LIPID-PEROXIDATION AND ENDOTHELIAL-CELL INJURY - IMPLICATIONS IN ATHEROSCLEROSIS [J].

HENNIG, B ;

CHOW, CK .

FREE RADICAL BIOLOGY AND MEDICINE, 1988, 4 (02) :99-106

[7] PLASMA ANTIOXIDANTS AND LIPID-PEROXIDATION PRODUCTS IN DUCHENNE MUSCULAR-DYSTROPHY [J].

HUNTER, MIS ;

MOHAMED, JB .

CLINICA CHIMICA ACTA, 1986, 155 (02) :123-131

[8] LIPID-PEROXIDATION AND PROTECTIVE ENZYMES DURING MYOCARDIAL-INFARCTION [J].

LOEPER, J ;

GOY, J ;

ROZENSZTAJN, L ;

BEDU, O ;

MOISSON, P .

CLINICA CHIMICA ACTA, 1991, 196 (2-3) :119-125

[9]

RICHARD MJ, 1992, CLIN CHEM, V38, P704

[10] RELATIONSHIP BETWEEN OXYGEN-METABOLISM, AGING AND DEVELOPMENT [J].

SOHAL, RS ;

ALLEN, RG .

ADVANCES IN FREE RADICAL BIOLOGY AND MEDICINE, 1986, 2 (01) :117-160

← 1 2 →