CONGENITAL ANEMIA AFTER TRANSPLACENTAL B19 PARVOVIRUS INFECTION

被引：103

作者：

BROWN, KE

GREEN, SW

DEMAYOLO, JA

BELLANTI, JA

SMITH, SD

SMITH, TJ

YOUNG, NS

机构：

[1] GEORGETOWN UNIV,SCH MED,INT CTR INTERDISCIPLINARY STUDIES IMMUNOL,WASHINGTON,DC

[2] UNIV CHICAGO,MED CTR,PEDIAT HEMATOL ONCOL SECT,CHICAGO,IL 60637

[3] CLIN HEMATOL ONCOL ASSOCIATES,DENVER,CO

[4] PRESBYTERIAN ST LUKES HOSP,ROCKY MT CHILDRENS CANC CTR,DENVER,CO

来源：

LANCET | 1994年 / 343卷 / 8902期

关键词：

D O I：

10.1016/S0140-6736(94)90011-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report three children with congenital anaemia after intrauterine infection with B19 parvovirus. All the fetuses developed hydrops fetails that was treated by blood transfusion. After delivery the infants had hypo-gammaglobulinaemia. In three, sera lacked B19 but viral DNA was found in bone marrow. All were treated with immunoglobulin. One child died and B19 was found in various tissues. In the other two cases, virus could no longer be detected after therapy but the patients remain persistently anaemic. Persistent B19 infection should be suspected in infants with congenital red-cell aplasia.

引用

页码：895 / 896

页数：2

共 9 条

[1] RAPID AND SIMPLE METHOD FOR PURIFICATION OF NUCLEIC-ACIDS [J].