HIGHLY EFFICIENT RESOLUTION OF BENZOPYRANO[4,3-C]ISOXAZOLIDINE DERIVATIVES - VERSATILE CHIRAL AUXILIARIES FOR ASYMMETRIC ALKYLATION

被引：16

作者：

ABIKO, A ^{[1
]}

DAVIS, WM ^{[1
]}

MASAMUNE, S ^{[1
]}

机构：

[1] MIT,DEPT CHEM,CAMBRIDGE,MA 02139

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0957-4166(95)00162-I

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Benzopyrano[4,3-c]isoxazolidine derivatives, newly developed chiral auxiliaries for asymmetric alkylation, were synthesized and resolved in a unique manner. Resolution could be executed so efficiently that both enantiomers were obtained with a single resolving reagent in excellent yields.

引用

收藏

页码：1295 / 1300

页数：6

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