P53 AND RB - THEIR CELLULAR ROLES

被引：71

作者：

PICKSLEY, SM

LANE, DP

机构：

[1] Dundee University, Dundee

来源：

CURRENT OPINION IN CELL BIOLOGY | 1994年 / 6卷 / 06期

关键词：

D O I：

10.1016/0955-0674(94)90056-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Within the past year, considerable new insights have been gained into the roles the p53 and retinoblastoma tumour suppressors play in determining the fate of cells through their regulation of cell cycle progression, apoptosis and gene expression. Key advances have been achieved in the identification and characterization of functional domains and through functional knockout studies.

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页码：853 / 858

页数：6

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