The parallel visual motion inputs into areas V1 and V5 of human cerebral cortex

被引:201
作者
ffytche, DH
Guy, CN
Zeki, S
机构
[1] UCL, DEPT ANAT, LONDON, ENGLAND
[2] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED, BLACKETT LAB, DEPT PHYS, LONDON SW7 2BZ, ENGLAND
基金
英国惠康基金;
关键词
EEG; magnetoencephalogram; motion evoked response; V1; V5; parallel input; dynamic parallelism;
D O I
10.1093/brain/118.6.1375
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Published clinical evidence has led us to hypothesize that there are parallel pathways which lead to the striate (V1) and prestriate cortex in the human brain. We have used the technique of visually evoked EEG coupled to magnetoencephalography (MEG) to test our hypothesis, by detecting the timing of arrival of signals into these visual areas, using published PET evidence to guide us in the location of the evoked response sources. We found that, if the moving stimulus has a speed of 22 degrees s(-1), signals arrive in V5 before V1; with speeds of <6 degrees s(-1), signals arrive in V1 first. We conclude that, in addition to the classical picture of a sequential input to prestriate cortex through V1, there is also a fast parallel input which by-passes V1. The parallelism manifests itself only as a function of the characteristics of the visual stimulus, a phenomenon we describe as dynamic parallelism. The results obtained help us explain the residual motion vision of patients with lesions in V1 or V5.
引用
收藏
页码:1375 / 1394
页数:20
相关论文
共 77 条
[1]   INTRACEREBRAL PROPAGATION OF INTERICTAL ACTIVITY IN PARTIAL EPILEPSY - IMPLICATIONS FOR SOURCE LOCALIZATION [J].
ALARCON, G ;
GUY, CN ;
BINNIE, CD ;
WALKER, SR ;
ELWES, RDC ;
POLKEY, CE .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1994, 57 (04) :435-449
[2]   MOTION ADAPTATION GOVERNS THE SHAPE OF MOTION-EVOKED CORTICAL POTENTIALS [J].
BACH, M ;
ULLRICH, D .
VISION RESEARCH, 1994, 34 (12) :1541-1547
[3]  
Balish M, 1990, Adv Neurol, V54, P79
[4]   CONSCIOUS VISUAL-PERCEPTION WITHOUT V1 [J].
BARBUR, JL ;
WATSON, JDG ;
FRACKOWIAK, RSJ ;
ZEKI, S .
BRAIN, 1993, 116 :1293-1302
[5]   THE CONSEQUENCES OF INACTIVATING AREAS V1 AND V5 ON VISUAL-MOTION PERCEPTION [J].
BECKERS, G ;
ZEKI, S .
BRAIN, 1995, 118 :49-60
[6]   A SHORT LATENCY CORTICAL COMPONENT OF THE FOVEAL VEP IS REVEALED BY HEMIFIELD STIMULATION [J].
BODISWOLLNER, I ;
BRANNAN, JR ;
NICOLL, J ;
FRKOVIC, S ;
MYLIN, LH .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1992, 84 (03) :201-208
[7]  
BRINDLEY GS, 1972, J PHYSIOL-LONDON, V225, pP1
[8]  
Bullier Jean, 1994, Cerebral Cortex, V10, P301
[9]   RECOMMENDED STANDARDS FOR ELECTRORETINOGRAMS AND VISUAL-EVOKED POTENTIALS - REPORT OF AN IFCN COMMITTEE [J].
CELESIA, GG ;
BODISWOLLNER, I ;
CHATRIAN, GE ;
HARDING, GFA ;
SOKOL, S ;
SPEKREIJSE, H .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1993, 87 (06) :421-436
[10]   VISUAL EVOKED-POTENTIALS AND POSITRON EMISSION TOMOGRAPHIC MAPPING OF REGIONAL CEREBRAL BLOOD-FLOW AND CEREBRAL METABOLISM - CAN THE NEURONAL POTENTIAL GENERATORS BE VISUALIZED [J].
CELESIA, GG ;
POLCYN, RD ;
HOLDEN, JE ;
NICKLES, RJ ;
GATLEY, JS ;
KOEPPE, RA .
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 1982, 54 (03) :243-256