SEQUENCE OF A PUTATIVE TRANSPORTER FROM RABBIT KIDNEY RELATED TO THE NA+/GLUCOSE COTRANSPORTER GENE FAMILY

被引：7

作者：

PAJOR, AM

机构：

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 1994年 / 1194卷 / 02期

关键词：

COTRANSPORT; SODIUM ION/GLUCOSE COTRANSPORTER; GLUCOSE TRANSPORT; CDNA SEQUENCE; (KIDNEY);

D O I：

10.1016/0005-2736(94)90319-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A 2 kb cDNA, RK-D, was isolated from a rabbit renal library by hybridization with the Na+/glucose cotransporter (SGLT1) cDNA. The mRNA for RK-D is also approximately 2 kb and is found predominantly in kidney. The RK-D cDNA encodes a protein of 597 amino acids related in sequence to the SGLT family of sodium-coupled transporters, all of which are related to the Na+/glucose cotransporter, SGLT1. Because of the high sequence similarity and conservation of 'signature' family features, it is very likely that RK-D encodes a Na+-dependent cotransporter.

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页码：349 / 351

页数：3

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