MOLECULAR PHARMACOLOGICAL ASPECTS OF HISTAMINE-RECEPTORS

被引：304

作者：

LEURS, R ^{[1
]}

SMIT, MJ ^{[1
]}

TIMMERMAN, H ^{[1
]}

机构：

[1] FREE UNIV AMSTERDAM, DEPT PHARMACOCHEM, LEIDEN AMSTERDAM CTR DRUG RES, 1081 HV AMSTERDAM, NETHERLANDS

来源：

PHARMACOLOGY & THERAPEUTICS | 1995年 / 66卷 / 03期

关键词：

HISTAMINE RECEPTORS; SELECTIVE AGONISTS AND ANTAGONISTS; MOLECULAR BIOLOGY; SIGNAL TRANSDUCTION;

D O I：

10.1016/0163-7258(95)00006-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In this article, we review the recent developments in the field of histamine research. Besides the description of pharmacological tools for the H-1, H-2 and H-3 receptor, specific attention is paid to both the molecular aspects of the receptor proteins, including the recent cloning of the receptor genes, and their respective signal transduction mechanisms.

引用

页码：413 / 463

页数：51

共 375 条

[1] HISTAMINE STIMULATION OF CYCLIC-AMP ACCUMULATION IN ASTROCYTE-ENRICHED AND NEURONAL PRIMARY CULTURES FROM RAT-BRAIN [J].

AGULLO, L ;

PICATOSTE, F ;

GARCIA, A .

JOURNAL OF NEUROCHEMISTRY, 1990, 55 (05) :1592-1598

[2] SOME FEATURES OF THE SPASMOGENIC ACTIONS OF ACETYLCHOLINE AND HISTAMINE IN GUINEA-PIG ISOLATED TRACHEALIS [J].

AHMED, F ;

FOSTER, RW ;

SMALL, RC ;

WESTON, AH .

BRITISH JOURNAL OF PHARMACOLOGY, 1984, 83 (01) :227-233

[3] SELECTIVE DISPLACEMENT OF [H-3] MEPYRAMINE FROM PERIPHERAL VS CENTRAL-NERVOUS-SYSTEM RECEPTORS BY LORATADINE, A NONSEDATING ANTIHISTAMINE [J].

AHN, HS ;

BARNETT, A .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1986, 127 (1-2) :153-155

[4] DIFFERENTIAL-EFFECTS OF ELEVATED CALCIUM-ION CONCENTRATIONS ON INOSITOL PHOSPHOLIPID RESPONSES IN MOUSE AND RAT CEREBRAL CORTICAL SLICES [J].

ALEXANDER, SPH ;

HILL, SJ ;

KENDALL, DA .

BIOCHEMICAL PHARMACOLOGY, 1990, 40 (08) :1793-1799

[5] THE ROLE OF CALCIUM IN THE CYCLIC-AMP RESPONSE TO HISTAMINE IN RABBIT CEREBRAL CORTICAL SLICES [J].

ALGADI, M ;

HILL, SJ .

BRITISH JOURNAL OF PHARMACOLOGY, 1987, 91 (01) :213-222

[6]

AMBLER SK, 1988, J BIOL CHEM, V263, P1952

[7] CHARACTERISTICS OF HISTAMINE TACHYPHYLAXIS IN CANINE TRACHEAL SMOOTH-MUSCLE - POSSIBLE PROSTAGLANDIN MEDIATED PHENOMENON [J].

ANDERSON, WH ;

KRZANOWSKI, JJ ;

POLSON, JB ;

SZENTIVANYI, A .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1979, 308 (02) :117-125

[8] AUTO-INHIBITION OF BRAIN HISTAMINE-RELEASE MEDIATED BY A NOVEL CLASS (H-3) OF HISTAMINE-RECEPTOR [J].

ARRANG, JM ;

GARBARG, M ;

SCHWARTZ, JC .

NATURE, 1983, 302 (5911) :832-837

[9] AUTO-REGULATION OF HISTAMINE-RELEASE IN BRAIN BY PRESYNAPTIC H-3-RECEPTORS [J].

ARRANG, JM ;

GARBARG, M ;

SCHWARTZ, JC .

NEUROSCIENCE, 1985, 15 (02) :553-562

[10] STEREOSELECTIVITY OF THE HISTAMINE H3-PRESYNAPTIC AUTORECEPTOR [J].

ARRANG, JM ;

SCHWARTZ, JC ;

SCHUNACK, W .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1985, 117 (01) :109-114

← 1 2 3 4 5 6 7 8 9 10 →