MULTIANALYTE MICROELECTRONIC BIOSENSORS

被引:51
作者
HIN, BFYY [1 ]
SETHI, RS [1 ]
LOWE, CR [1 ]
机构
[1] PLESSEY RES CASWELL LTD,ALLEN CLARKE RES CTR,TOWCESTER NN12 8EQ,NORTHANTS,ENGLAND
关键词
D O I
10.1016/0925-4005(90)80271-Z
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This paper describes the use of monolithic silicon technology for the fabrication of multi-analyte miniature biosensors for clinical applications. Electrochemically generated conducting polymers were used to entrap enzyme at the sensing microelectrode surfaces. This enzyme immobilisation procedure allows precise control of the spatial distribution of the enzyme and can, therefore, be applied to the fabrication of multi-electrode multi-analyte biosensors. The operation of two dual-enzyme microelectronic biosensors is described for the detection of glucose/galactose and glucose/urea respectively. © 1990.
引用
收藏
页码:550 / 554
页数:5
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