APPLICATION OF DIRECT ONLINE COUPLING OF HPLC AND SFC WITH (1)HNMR SPECTROSCOPY FOR THE INVESTIGATION OF MONOMERIC ACRYLATES

被引：13

作者：

ALBERT, K

BRAUMANN, U

STRECK, R

SPRAUL, M

ECKER, R

机构：

[1] DOW DEUTSCHLAND INC,D-77836 RHEINMUNSTER,GERMANY

[2] BRUKER ANALYT MESSTECHN,D-76287 RHEINSTETTEN,GERMANY

[3] HEWLETT PACKARD GMBH,D-76337 WALDBRONN,GERMANY

来源：

FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY | 1995年 / 352卷 / 05期

关键词：

D O I：

10.1007/BF00323378

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The separation of monomeric acrylates was perfomed with High Performance Liquid Chromatography (HPLC) and Supercritical Fluid Chromatography (SFC). A direct on-line structural assignment of all compounds by continuous-flow H-1 NMR spectroscopy is possible with both separation techniques. The direct SFC-NMR coupling offers the advantage that the recorded continuous-flow H-1 NMR spectrum is not obscured by solvent signals.

引用

页码：521 / 528

页数：8

共 16 条

[1] INVESTIGATION OF A CYCLOPROPYL-CONTAINING DRUG BY ONLINE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY NUCLEAR MAGNETIC-RESONANCE
ALBERT, K
KUNST, M
BAYER, E
DEJONG, HJ
GENISSEL, P
SPRAUL, M
BERMEL, W
[J]. ANALYTICAL CHEMISTRY, 1989, 61 (07) : 772 - 775
[2] REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY NUCLEAR MAGNETIC-RESONANCE ONLINE COUPLING WITH SOLVENT NON-EXCITATION
ALBERT, K
KUNST, M
BAYER, E
SPRAUL, M
BERMEL, W
[J]. JOURNAL OF CHROMATOGRAPHY, 1989, 463 (02): : 355 - 363
[3] ONLINE COUPLING OF SUPERCRITICAL-FLUID CHROMATOGRAPHY AND PROTON HIGH-FIELD NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY
ALBERT, K
BRAUMANN, U
TSENG, LH
NICHOLSON, G
BAYER, E
SPRAUL, M
HOFMANN, M
DOWLE, C
CHIPPENDALE, M
[J]. ANALYTICAL CHEMISTRY, 1994, 66 (19) : 3042 - 3046
[4] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY - NUCLEAR MAGNETIC-RESONANCE ONLINE COUPLING
ALBERT, K
BAYER, E
[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 1988, 7 (08) : 288 - 293
[5] ALBERT K, 1988, THESIS TUBINGEN U
[6] ALBERT K, 1994, IN PRESS FRONTIERS A
[7] Albert K, 1992, HPLC DETECTION NEWER, P197
[8] EXAMPLES OF APPLICATION OF DIRECT HPLC-NMR-COUPLING WITH HIGH-RESOLUTION
BAYER, E
ALBERT, K
NIEDER, M
GROM, E
AN, Z
[J]. FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE CHEMIE, 1980, 304 (2-3): : 111 - 116
[9] ONLINE COUPLING OF LIQUID-CHROMATOGRAPHY AND HIGH-FIELD NUCLEAR MAGNETIC-RESONANCE SPECTROMETRY
BAYER, E
ALBERT, K
NIEDER, M
GROM, E
WOLFF, G
RINDLISBACHER, M
[J]. ANALYTICAL CHEMISTRY, 1982, 54 (11) : 1747 - 1750
[10] ONLINE COUPLING OF HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AND NUCLEAR MAGNETIC-RESONANCE
BAYER, E
ALBERT, K
NIEDER, M
GROM, E
[J]. JOURNAL OF CHROMATOGRAPHY, 1979, 186 (DEC): : 497 - 507

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