N-6-SUBSTITUTED N-ALKYLADENOSINE-5'-URONAMIDES - BIFUNCTIONAL LIGANDS HAVING RECOGNITION GROUPS FOR A1 AND A2 ADENOSINE RECEPTORS

被引：50

作者：

OLSSON, RA

KUSACHI, S

THOMPSON, RD

UKENA, D

PADGETT, W

DALY, JW

机构：

[1] UNIV S FLORIDA,COLL MED,DEPT INTERNAL MED,TAMPA,FL 33612

[2] UNIV S FLORIDA,COLL MED,DEPT BIOCHEM,TAMPA,FL 33612

[3] NIADDKD,BIOORGAN CHEM LAB,BETHESDA,MD 20205

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 09期

关键词：

D O I：

10.1021/jm00159a020

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1683 / 1689

页数：7

共 19 条

[1] ADENOSINE RECEPTORS IN BRAIN MEMBRANES - BINDING OF N6-CYCLOHEXYL[H-3]ADENOSINE AND 1,3-DIETHYL-8-[H-3]PHENYLXANTHINE [J].

BRUNS, RF ;

DALY, JW ;

SNYDER, SH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (09) :5547-5551

[2]

DALY JW, BIOCH PHARM

[3] SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME NEW N6-SUBSTITUTED PURINE NUCLEOSIDES [J].

FLEYSHER, MH ;

BLOCH, A ;

HAKALA, MT ;

NICHOL, CA .

JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (06) :1056-&

[4]

KUSACHI S, 1983, J PHARMACOL EXP THER, V227, P316

[5] DOG CORONARY-ARTERY ADENOSINE RECEPTOR - STRUCTURE OF THE N6-ARYL SUBREGION [J].

KUSACHI, S ;

THOMPSON, RD ;

YAMADA, N ;

DALY, DT ;

OLSSON, RA .

JOURNAL OF MEDICINAL CHEMISTRY, 1986, 29 (06) :989-996

[6] DOG CORONARY-ARTERY ADENOSINE RECEPTOR - STRUCTURE OF THE N-6-ALKYL SUBREGION [J].

KUSACHI, S ;

THOMPSON, RD ;

BUGNI, WJ ;

YAMADA, N ;

OLSSON, RA .

JOURNAL OF MEDICINAL CHEMISTRY, 1985, 28 (11) :1636-1643

[7] SUBCLASSES OF EXTERNAL ADENOSINE RECEPTORS [J].

LONDOS, C ;

COOPER, DMF ;

WOLFF, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (05) :2551-2554

[8] CORONARY VASOACTIVITY OF ADENOSINE IN THE CONSCIOUS DOG [J].

OLSSON, RA ;

KHOURI, EM ;

BEDYNEK, JL ;

MCLEAN, J .

CIRCULATION RESEARCH, 1979, 45 (04) :468-478

[9] MODIFICATION OF THE 5' POSITION OF PURINE NUCLEOSIDES .2. SYNTHESIS AND SOME CARDIOVASCULAR PROPERTIES OF ADENOSINE-5'-(N-SUBSTITUTED)CARBOXAMIDES [J].

PRASAD, RN ;

BARIANA, DS ;

FUNG, A ;

SAVIC, M ;

TIETJE, K ;

STEIN, HH ;

BRONDYK, H ;

EGAN, RS .

JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (03) :313-319

[10] MODIFICATION OF 5' POSITION OF PURINE NUCLEOSIDES .1. SYNTHESIS AND BIOLOGICAL PROPERTIES OF ALKYL ADENOSINE-5'-CARBOXYLATES [J].

PRASAD, RN ;

FUNG, A ;

TIETJE, K ;

STEIN, HH ;

BRONDYK, HD .

JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (10) :1180-1186

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