EFFECT OF NON-UNIFORM INITIAL-DRUG CONCENTRATION DISTRIBUTION ON THE KINETICS OF DRUG RELEASE FROM GLASSY HYDROGEL MATRICES

被引：94

作者：

LEE, PI ^{[1
]}

机构：

[1] CIBA GEIGY CORP, CENT RES, ARDSLEY, NY 10502 USA

来源：

关键词：

D O I：

10.1016/0032-3861(84)90082-X

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

引用

页码：973 / 978

页数：6

共 29 条

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Crank J., 1968, DIFFUSION POLYM

[5]

GOOD WR, 1976, POLYM DELIVERY SYSTE, P139

HELLER, J .

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HIGUCHI, T .

[9] SWELLING-CONTROLLED, CONSTANT RATE DELIVERY SYSTEMS [J].

HOPFENBERG, HB ;

HSU, KC .

HSIEH, DST ;

RHINE, WD ;

LANGER, R .