MULTIVARIATE GENETIC-ANALYSIS OF TWIN-FAMILY DATA ON FEARS - MX MODELS

被引：40

作者：

NEALE, MC ^{[1
]}

WALTERS, EE ^{[1
]}

EAVES, LJ ^{[1
]}

MAES, HH ^{[1
]}

KENDLER, KS ^{[1
]}

机构：

[1] VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DEPT HUMAN GENET,RICHMOND,VA 23298

来源：

BEHAVIOR GENETICS | 1994年 / 24卷 / 02期

关键词：

MULTIVARIATE GENETIC ANALYSIS; TWIN-FAMILY DATA; FEARS; MX MODELS; CULTURAL TRANSMISSION; GENETIC DOMINANCE; ASSORTATIVE MATING;

D O I：

10.1007/BF01067816

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

We describe the implementation of multivariate models of familial resemblance with the Mx package. The structural equation models allow for the effects of assortative mating, additive and dominant genes, common and specific environment, and both genetic and cultural transmission between generations. Two approaches are compared: a correlational one based on Fulker and a factor model described by Phillips and Fulker. Both are illustrated by application to published data on social fears and fear of leadership measured in monozygotic and dizygotic twins and their parents. In the example data, genetic dominance yields a more parsimonious explanation of the data than does cultural transmission, although neither is needed to obtain a good fit to the data. A model of reduced genetic correlation between generations also fits the data but has inherent limitations in this sample. Extensions to sex-limitation and more complex models are discussed.

引用

页码：119 / 139

页数：21

共 40 条

[1] FACTOR-ANALYSIS AND AIC [J].

AKAIKE, H .

PSYCHOMETRIKA, 1987, 52 (03) :317-332

[2] A LISREL-8 MODEL WITH CONSTRAINED PARAMETERS FOR TWIN AND ADOPTIVE FAMILIES [J].

CARDON, LR ;

FULKER, DW ;

JORESKOG, KG .

BEHAVIOR GENETICS, 1991, 21 (04) :327-350

[3]

CAREY G, 1986, AM J HUM GENET, V39, P775

[4]

EATON WW, 1991, PSYCHIATRIC DISORDER

[5] A THEORY OF DEVELOPMENTAL-CHANGE IN QUANTITATIVE PHENOTYPES APPLIED TO COGNITIVE-DEVELOPMENT [J].

EAVES, LJ ;

LONG, J ;

HEATH, AC .

BEHAVIOR GENETICS, 1986, 16 (01) :143-162

[6] MODEL-FITTING APPROACHES TO THE ANALYSIS OF HUMAN-BEHAVIOR [J].

EAVES, LJ ;

LAST, KA ;

YOUNG, PA ;

MARTIN, NG .

HEREDITY, 1978, 41 (DEC) :249-320

[7] ANALYZING TWIN RESEMBLANCE IN MULTISYMPTOM DATA - GENETIC APPLICATIONS OF A LATENT CLASS MODEL FOR SYMPTOMS OF CONDUCT DISORDER IN JUVENILE BOYS [J].

EAVES, LJ ;

SILBERG, JL ;

HEWITT, JK ;

RUTTER, M ;

MEYER, JM ;

NEALE, MC ;

PICKLES, A .

BEHAVIOR GENETICS, 1993, 23 (01) :5-19

[8] THE EFFECTS OF SOCIAL HOMOGAMY AND CULTURAL INHERITANCE ON THE COVARIANCES OF TWINS AND THEIR PARENTS - A LISREL MODEL [J].

EAVES, LJ ;

FULKER, DW ;

HEATH, AC .

BEHAVIOR GENETICS, 1989, 19 (01) :113-122

[9]

Eaves LJ, 1989, GENES CULTURE PERSON

[10]

Fisher R. A., 1919, Transactions of the Royal Society of Edinburgh, V52

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