ARE THE CORE PROTEINS OF THE MITOCHONDRIAL BC(1) COMPLEX EVOLUTIONARY RELICS OF A PROCESSING PROTEASE

被引：114

作者：

BRAUN, HP

SCHMITZ, UK

机构：

[1] Institut für Genbiologische Forschung GmbH, D-14195 Berlin

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1995年 / 20卷 / 05期

关键词：

D O I：

10.1016/S0968-0004(00)88999-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The so-called 'core' proteins of the respiratory cytochrome bc(1) complex and the two subunits of the mitochondrial processing peptidase (MPP) are structurally similar but their evolutionary relationship remains a mystery. Here, we present a model suggesting that the core proteins originated from an ancient proteolytic enzyme that was integrated into the bc(1) complex during early stages of endosymbiosis.

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页码：171 / 175

页数：5

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