IDENTIFICATION BY AMINO-ACID SEQUENCING OF 3 MAJOR REGULATORY PHOSPHORYLATION SITES ON RAT ACETYL-COA CARBOXYLASE

被引：246

作者：

MUNDAY, MR ^{[1
]}

CAMPBELL, DG ^{[1
]}

CARLING, D ^{[1
]}

HARDIE, DG ^{[1
]}

机构：

[1] UNIV DUNDEE,INST MED SCI,DEPT BIOCHEM,MRC,PROT PHOSPHORYLAT GRP,DUNDEE DD1 4HN,SCOTLAND

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1988年 / 175卷 / 02期

关键词：

D O I：

10.1111/j.1432-1033.1988.tb14201.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：331 / 338

页数：8

共 24 条

[1] EVIDENCE FOR PHOSPHORYLATION AND ACTIVATION OF ACETYL COA CARBOXYLASE BY A MEMBRANE-ASSOCIATED CYCLIC AMP-INDEPENDENT PROTEIN-KINASE - RELATIONSHIP TO THE ACTIVATION OF ACETYL COA CARBOXYLASE BY INSULIN [J].

BROWNSEY, RW ;

BELSHAM, GJ ;

DENTON, RM .

FEBS LETTERS, 1981, 124 (02) :145-150

[2] REGULATION OF ACETYL-COA CARBOXYLASE - IDENTITY OF SITES PHOSPHORYLATED IN INTACT-CELLS TREATED WITH ADRENALINE AND INVITRO BY CYCLIC AMP-DEPENDENT PROTEIN-KINASE [J].

BROWNSEY, RW ;

HARDIE, DG .

FEBS LETTERS, 1980, 120 (01) :67-70

[3] EVIDENCE THAT INSULIN ACTIVATES FAT-CELL ACETYL-COA CARBOXYLASE BY INCREASED PHOSPHORYLATION AT A SPECIFIC SITE [J].

BROWNSEY, RW ;

DENTON, RM .

BIOCHEMICAL JOURNAL, 1982, 202 (01) :77-86

[4]

BROWNSEY RW, 1987, ENZYMES B, V18, P123, DOI DOI 10.1016/S1874-6047(08)60256-5

[5] ISOLATION OF A CYCLIC-AMP-INDEPENDENT PROTEIN-KINASE FROM RAT-LIVER AND ITS EFFECT ON THE ENZYMATIC-ACTIVITY OF ACETYL-COA CARBOXYLASE [J].

CARLING, D ;

HARDIE, DG .

BIOCHEMICAL SOCIETY TRANSACTIONS, 1986, 14 (06) :1076-1077

[6] A COMMON BICYCLIC PROTEIN-KINASE CASCADE INACTIVATES THE REGULATORY ENZYMES OF FATTY-ACID AND CHOLESTEROL-BIOSYNTHESIS [J].

CARLING, D ;

ZAMMIT, VA ;

HARDIE, DG .

FEBS LETTERS, 1987, 223 (02) :217-222

[7] PROTEIN-PHOSPHORYLATION IN RAT MAMMARY ACINI AND IN CYTOSOL PREPARATIONS INVITRO - PHOSPHORYLATION OF ACETYL-COA CARBOXYLASE IS UNAFFECTED BY CYCLIC-AMP [J].

CLEGG, RA ;

WEST, DW ;

AITCHISON, RED .

BIOCHEMICAL JOURNAL, 1987, 241 (02) :447-454

[8] THE ROLE OF PROTEIN-PHOSPHORYLATION IN THE HORMONAL-CONTROL OF ENZYME-ACTIVITY [J].

COHEN, P .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1985, 151 (03) :439-448

[9] PURIFICATION AND PHYSICOCHEMICAL PROPERTIES OF ATP CITRATE (PRO-3S) LYASE FROM LACTATING RAT MAMMARY-GLAND AND STUDIES OF ITS REVERSIBLE PHOSPHORYLATION [J].

GUY, PS ;

COHEN, P ;

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EUROPEAN JOURNAL OF BIOCHEMISTRY, 1981, 114 (02) :399-405

[10]

Hardie D. G., 1984, Hormones and Cell Regulation, V8, P117

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