SIGNAL TRANSDUCTION ENZYMES OF VERTEBRATE PHOTORECEPTORS

被引：51

作者：

HURLEY, JB ^{[1
]}

机构：

[1] UNIV WASHINGTON, DEPT BIOCHEM, SEATTLE, WA 98195 USA

来源：

JOURNAL OF BIOENERGETICS AND BIOMEMBRANES | 1992年 / 24卷 / 02期

关键词：

PHOTOTRANSDUCTION; VISION; RODS AND CONES; G-PROTEINS; TRANSDUCIN; SIGNAL TRANSDUCTION; RECOVERIN; KINASES; CHANNELS; CALCIUM;

D O I：

10.1007/BF00762680

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A flash of light initiates a cascade of biochemical reactions inside vertebrate photoreceptor cells, culminating in hydrolysis of intracellular cyclic GMP and hyperpolarization of the cell. The cell recovers by shutting down this cascade and resynthesizing cGMP. Many of the reactions responsible for the excitation and recovery phases of the photoresponse have been identified. Here I review some characteristics of the proteins that participate in these reactions.

引用

页码：219 / 226

页数：8

共 74 条

[1] ARSHAVSKY VY, 1991, J BIOL CHEM, V266, P18530
[2] ATON BR, 1984, J GEN PHYSIOL, V85, P83
[3] BAYLOR DA, 1987, INVEST OPHTH VIS SCI, V28, P34
[4] BEAVO JA, 1988, ADV SEC MESS PHOSPH, V22, P1
[5] BINDER BM, 1990, J BIOL CHEM, V265, P15333
[6] BREITMAN ML, 1991, J BIOL CHEM, V266, P15505
[7] EXPRESSION IN BACTERIA OF FUNCTIONAL INHIBITORY SUBUNIT OF RETINAL ROD CGMP PHOSPHODIESTERASE
BROWN, RL
STRYER, L
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (13) : 4922 - 4926
[8] A NOVEL MULTIGENE FAMILY MAY ENCODE ODORANT RECEPTORS - A MOLECULAR-BASIS FOR ODOR RECOGNITION
BUCK, L
AXEL, R
[J]. CELL, 1991, 65 (01) : 175 - 187
[9] COOK NJ, 1988, J BIOL CHEM, V263, P11382
[10] IDENTIFICATION, PURIFICATION, AND FUNCTIONAL RECONSTITUTION OF THE CYCLIC GMP-DEPENDENT CHANNEL FROM ROD PHOTORECEPTORS
COOK, NJ
HANKE, W
KAUPP, UB
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (02) : 585 - 589

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