SIDE-CHAIN INTRODUCTION IN 16-BETA-ACETOXY-17-OXO-ANDROSTANES

被引：7

作者：

DOLLER, D ^{[1
]}

GROS, EG ^{[1
]}

机构：

[1] UNIV BUENOS AIRES,FAC CIENCIAS EXACTAS & NAT,DEPT QUIM ORGAN,CIUDAD UNIV PAB 11,RA-1428 BUENOS AIRES,ARGENTINA

来源：

SYNTHETIC COMMUNICATIONS | 1990年 / 20卷 / 20期

关键词：

D O I：

10.1080/00397919008051534

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction between lithium enolates derived from t-butyl esters and l6β-acetoxy-17-oxo-androstane derivatives allowed regiospecific introduction of the side-chain only on C-17 of the steroid nucleus. © 1990, Taylor & Francis Group, LLC. All rights reserved.

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页码：3115 / 3124

页数：10

相关论文

共 16 条

[1] PYRIDINE-INDUCED SOLVENT SHIFTS IN NUCLEAR MAGNETIC RESONANCE SPECTRA OF HYDROXYLIC COMPOUNDS [J].

DEMARCO, PV ;

FARKAS, E ;

DODDRELL, D ;

MYLARI, BL ;

WENKERT, E .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1968, 90 (20) :5480-&

[2] C-13 NMR SPECTROSCOPIC STUDY OF THE REARRANGEMENT OF 16-BETA-HYDROXY-17-OXO STEROIDS TO 17-BETA-HYDROXY-16-OXO ISOMERS [J].

DOLLER, D ;

GROS, EG .

MAGNETIC RESONANCE IN CHEMISTRY, 1988, 26 (07) :539-541

[3] DISSIMILAR BEHAVIOR OF 3-BETA,16-ALPHA-DIHYDROXY-5-ALPHA-ANDROSTAN-17-ONE DIACETATE UNDER BASIC AND ACIDIC CONDITIONS [J].

DOLLER, D ;

GROS, EG .

HELVETICA CHIMICA ACTA, 1989, 72 (06) :1241-1247

[4]

EVANS DA, 1982, TOP STEREOCHEM, V13, P1, DOI DOI 10.1002/9780470147221.CHL

[5]

FIESER LF, 1959, STEROIDS

[6]

IWASAKI M, 1967, STEROIDS, V9, P373

[7] THE ACTION OF LEAD TETRAACETATE ON AN ENOL ACETATE - THE EPIMERIC 16-ACETOXY DERIVATIVES OF EPIANDROSTERONE ACETATE, THEIR INTERCONVERSION AND REARRANGEMENT [J].

JOHNSON, WS ;

GASTAMBIDE, B ;

PAPPO, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1957, 79 (08) :1991-1994

[8] THE SYNTHESIS OF THE STEROIDAL SAPOGENINS [J].

MAZUR, Y ;

DANIELI, N ;

SONDHEIMER, F .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1960, 82 (22) :5889-5908

[9]

NUMAZAWA M, 1987, CHEM PHARM BULL, V35, P4763

[10] SYNTHESIS OF GAMMA-LACTONE RING FUSED TO STEROIDAL RING-D OF SALAMANDER ALKALOIDS [J].

OKA, K ;

HARA, S .

JOURNAL OF ORGANIC CHEMISTRY, 1978, 43 (23) :4408-4410