EFFECT OF AGE ON THE SENSITIVITY OF UPPER AIRWAY REFLEXES

被引：43

作者：

ERSKINE, RJ ^{[1
]}

MURPHY, PJ ^{[1
]}

LANGTON, JA ^{[1
]}

SMITH, G ^{[1
]}

机构：

[1] LEICESTER ROYAL INFIRM,DEPT ANAESTHESIA,LEICESTER LE1 5WW,ENGLAND

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1993年 / 70卷 / 05期

关键词：

AGE FACTORS; AIRWAY; REFLEX SENSITIVITY;

D O I：

10.1093/bja/70.5.574

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We have recorded the threshold concentration of inhaled ammonia vapour required to elicit reflex glottic closure (NHTR) in 102 healthy, non-smoking volunteers (39 female) aged 17-96 yr in order to assess the effect of age upon upper airway reflex sensitivity. A single measurement of sensitivity was made in each subject using a system delivering small concentrations of ammonia vapour for single intermittent breaths to the upper airway and recording glottic closure using an inspiratory pneumotachograph. We found a strong positive correlation between age and NH3TR, indicating a decrease in upper airway reflex sensitivity with increasing age.

引用

页码：574 / 575

页数：2

共 6 条

[1]

BRIZZEE KR, 1979, SENSORY SYSTEMS COMM, V10, P58

[2] ANESTHESIA FOR THE GERIATRIC-PATIENT [J].

DAVENPORT, HT .

CANADIAN ANAESTHETISTS SOCIETY JOURNAL, 1983, 30 (03) :S51-S55

[3]

ERSKINE RJ, 1992, 10TH WORLD C AN

[4] MEASUREMENT OF THE SENSITIVITY OF UPPER AIRWAY REFLEXES [J].

LANGTON, JA ;

MURPHY, PJ ;

BARKER, P ;

KEY, A ;

SMITH, G .

BRITISH JOURNAL OF ANAESTHESIA, 1993, 70 (02) :126-130

[5] PROGRESSIVE LOSS OF PROTECTIVE REFLEXES IN THE AIRWAY WITH THE ADVANCE OF AGE [J].

PONTOPPIDAN, H ;

BEECHER, HK .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1960, 174 (18) :2209-2213

[6]

ROSENBERG SI, 1989, ARCH OTOLARYNGOL, V115, P78

← 1 →