BREAST-CANCER AMONG WOMEN EXPOSED TO POLYBROMINATED BIPHENYLS

被引：37

作者：

HENDERSON, AK ^{[1
]}

ROSEN, D ^{[1
]}

MILLER, GL ^{[1
]}

FIGGS, LW ^{[1
]}

ZAHM, SH ^{[1
]}

SIEBER, SM ^{[1
]}

HUMPHREY, HEB ^{[1
]}

SINKS, T ^{[1
]}

机构：

[1] CTR DIS CONTROL & PREVENT,NATL CTR ENVIRONM HLTH,DIV ENVIRONM HAZARD & HLTH EFFECTS,ATLANTA,GA

来源：

EPIDEMIOLOGY | 1995年 / 6卷 / 05期

关键词：

POLYBROMINATED BIPHENYLS; BREAST CANCER; MICHIGAN; ORGANOHALIDES; FOOD CONTAMINATION; CASE-CONTROL STUDY; BIOMARKERS; COHORT STUDY;

D O I：

10.1097/00001648-199509000-00014

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We conducted a nested case-control study with 1,925 women enrolled in a polybrominated biphenyl (PBB) registry to examine the association between breast cancer and serum PBBs. Twenty women who developed breast cancer were matched to 290 control subjects on sex, race, and age. Women with serum PBB levels of 2.0-3.0 parts per billion (ppb) [odds ratio (OR) = 3.5; 95% confidence interval (CI) = 0.9-13] or 4.0 ppb or greater (OR = 3.1; 95% CI = 0.8-12) had a higher estimated risk for breast cancer than women with less than 2.0 ppb. The odds ratios were unchanged when available breast cancer risk factors were included in the analysis.

引用

页码：544 / 546

页数：3

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