ASTEMIZOLE-INDUCED VENTRICULAR ARRHYTHMIAS - AN UNEXPECTED CAUSE OF CONVULSIONS

被引：26

作者：

CLARK, A ^{[1
]}

LOVE, H ^{[1
]}

机构：

[1] UNIV MANCHESTER,MANCHESTER ROYAL INFIRM,DEPT CARDIOL,OXFORD RD,MANCHESTER M13 9WL,LANCS,ENGLAND

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 1991年 / 33卷 / 01期

关键词：

Astemizole; Mobitz type two heart block; QT prolongation;

D O I：

10.1016/0167-5273(91)90166-M

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Antihistamines are commonly used drugs. The more recent additions to the formulary are less sedative, but have been implicated as a cause of ventricular arrhythmias. We report a case in which a deliberate overdose of astemizole was associated with Mobitz type two heart block and prolongation of the QT interval, causing the so-called torsade-de-pointes ventricular tachycardia.

引用

页码：165 / 167

页数：3