DE-NOVO DESIGN AND SYNTHESIS OF 4 ALPHA-HELIX BUNDLE PROTEINS WITH FLAVIN FUNCTION

被引：25

作者：

MIHARA, H ^{[1
]}

TOMIZAKI, KY ^{[1
]}

NISHINO, N ^{[1
]}

FUJIMOTO, T ^{[1
]}

机构：

[1] KYUSHU INST TECHNOL, FAC ENGN, DEPT APPL CHEM, KITAKYUSHU 804, JAPAN

来源：

CHEMISTRY LETTERS | 1993年 / 09期

关键词：

D O I：

10.1246/cl.1993.1533

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Four alpha-helix bundle proteins containing flavin moieties (7-acetyl-10-methylisoalloxazine) were de novo designed and synthesized. The artificial proteins could effectively catalyze the oxidation of dihydronicotinamides under controlled conditions for bundle structure.

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页码：1533 / 1536

页数：4

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