LIQUID-CHROMATOGRAPHIC DETERMINATION OF PINACIDIL, A NEW ANTIHYPERTENSIVE DRUG, AND ITS MAJOR METABOLITE, PINACIDIL N-OXIDE, IN PLASMA

被引：12

作者：

HAMILTON, M

FARID, KZ

HENRY, DP

机构：

来源：

JOURNAL OF CHROMATOGRAPHY | 1986年 / 375卷 / 02期

关键词：

D O I：

10.1016/S0378-4347(00)83728-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

引用

页码：359 / 367

页数：9

共 12 条

[1] N''-CYANO-N-4-PYRIDYL-N'-1,2,2-TRIMETHYLPROPYLGUANIDINE, MONOHYDRATE (P 1134) - A NEW, POTENT VASODILATOR [J].

ARRIGONIMARTELLI, E ;

NIELSEN, CK ;

OLSEN, UB ;

PETERSEN, HJ .

EXPERIENTIA, 1980, 36 (04) :445-447

[2] PINACIDIL, A NEW VASODILATOR - PHARMACOKINETICS AND PHARMACODYNAMICS OF A NEW RETARDED RELEASE TABLET IN ESSENTIAL-HYPERTENSION [J].

CARLSEN, JE ;

KARDEL, T ;

JENSEN, HA ;

TANGO, M ;

TRAPJENSEN, J .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 25 (04) :557-561

[3] ACUTE HEMODYNAMIC-EFFECTS OF PINACIDIL AND HYDRALAZINE IN ESSENTIAL-HYPERTENSION [J].

CARLSEN, JE ;

KARDEL, T ;

LUND, JO ;

MCNAIR, A ;

TRAPJENSEN, J .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1985, 37 (03) :253-259

[4] METABOLISM OF THE NEW ANTIHYPERTENSIVE AGENT PINACIDIL IN RAT, DOG AND MAN [J].

EILERTSEN, E ;

MAGNUSSEN, MP ;

PETERSEN, HJ ;

RASTRUPANDERSEN, N ;

SORENSEN, H ;

ARRIGONIMARTELLI, E .

XENOBIOTICA, 1982, 12 (03) :187-196

[5] PHARMACOKINETICS AND DISTRIBUTION OF THE NEW ANTIHYPERTENSIVE AGENT PINACIDIL IN RAT, DOG AND MAN [J].

EILERTSEN, E ;

HART, JW ;

MAGNUSSEN, MP ;

SORENSEN, H ;

ARRIGONIMARTELLI, E .

XENOBIOTICA, 1982, 12 (03) :177-185

[6] N''-CYANO-N-4-PYRIDYL-N'-1,2,2-TRIMETHYL-PROPYLGUANIDINE, A NEW VASODILATING AGENT - ACUTE EFFECT ON BLOOD-PRESSURE AND PHARMACOKINETICS IN HYPERTENSIVE PATIENTS [J].

KARDEL, T ;

HILDEN, T ;

CARLSEN, J ;

TRAPJENSEN, J .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1981, 3 (05) :1002-1007

[7] PINACIDIL, A NEW VASODILATOR, IN THE TREATMENT OF PATIENTS WITH MODERATE TO SEVERE HYPERTENSION [J].

KOLIOPOULOS, K ;

PAPADOYANNIS, DE ;

KARATZAS, NB .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 27 (03) :287-289

[8]

OLSEN UB, 1983, EUR J PHARMACOL, V88, P389

[9] PRELIMINARY EVALUATION OF PINACIDIL IN HYPERTENSION [J].

RAMSAY, LE ;

FREESTONE, S .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1983, 16 (03) :336-338

[10] HEMODYNAMIC CHARACTERIZATION OF PINACIDIL IN RATS - COMPARISON WITH HYDRALAZINE [J].

THOOLEN, MJMC ;

VANMEEL, JCA ;

WILFFERT, B ;

TIMMERMANS, PBMWM ;

VANZWIETEN, PA .

PHARMACOLOGY, 1983, 27 (05) :245-254

← 1 2 →