MOLECULAR MECHANISMS OF PROTEIN-MEDIATED MEMBRANE-FUSION

被引：37

作者：

HUGHSON, FM

机构：

[1] Department of Molecular Biology, Princeton University, Princeton

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1995年 / 5卷 / 04期

关键词：

D O I：

10.1016/0959-440X(95)80036-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two recent X-ray structures shed new light on the molecular mechanisms by which viral proteins mediate membrane fusion. In both cases it is clear that the fusion proteins are capable of dramatic conformational rearrangements. Studies of the intracellular fusion machinery used in vesicular transport have also advanced rapidly, although high-resolution structural information is not yet available.

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收藏

页码：507 / 513

页数：7

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