CLONING AND FUNCTIONAL EXPRESSION OF A TEA-SENSITIVE A-TYPE POTASSIUM CHANNEL FROM RAT-BRAIN

被引：128

作者：

SCHROTER, KH

RUPPERSBERG, JP

WUNDER, F

RETTIG, J

STOCKER, M

PONGS, O

机构：

[1] MAX PLANCK INST MED RES,ZELLPHYSIOL ABT,JAHNSTR 29,W-6900 HEIDELBERG 1,GERMANY

[2] RUHR UNIV BOCHUM,LEHRSTUHL BIOCHEM,W-4630 BOCHUM,GERMANY

来源：

FEBS LETTERS | 1991年 / 278卷 / 02期

关键词：

CDNA CLONING; CRNA EXPRESSION; POTASSIUM CHANNEL; A-TYPE K+ CHANNEL; IA CHANNEL;

D O I：

10.1016/0014-5793(91)80119-N

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A rat brain cDNA (Raw3) related to the Drosophila Shaw K+ channel family has been characterized. Raw3 cRNA leads to the formation of TEA-insensitive, fast inactivating (A-type) K+ channels when injected into Xenopus laevis oocytes. Raw3 channels have markedly different properties from the previously cloned rat A-type K+ channel RCK4. Raw3 channels operate in the positive voltage range.

引用

页码：211 / 216

页数：6

共 24 条

[1] SCREENING GAMMAGT RECOMBINANT CLONES BY HYBRIDIZATION TO SINGLE PLAQUES INSITU [J].