THERMOSPRAY LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY OF POLAR BETA-BLOCKING DRUGS - PRELIMINARY-RESULTS

被引：6

作者：

LELOUX, MS

NIESSEN, WMA

VANDERHOEVEN, RAM

机构：

[1] STATE UNIV UTRECHT,NETHERLANDS INST DRUGS & DOPING RES,3521 GH UTRECHT,NETHERLANDS

[2] LEIDEN UNIV,CTR BIOPHARMACEUT,DIV ANALYT CHEM,2300 RA LEIDEN,NETHERLANDS

来源：

BIOLOGICAL MASS SPECTROMETRY | 1991年 / 20卷 / 10期

关键词：

D O I：

10.1002/bms.1200201010

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The use of thermospray liquid chromatography for the screening of polar beta-blocking drugs is evaluated. The influence of instrumental parameters on the fragmentation pattern of labetalol, acebutolol, diacetolol, sotalol and atenolol is described. A short biomedical application is presented.

引用

页码：647 / 649

页数：3

共 6 条

[1]

BOWERS LD, 1989, CLIN CHEM, V35, P1282

[2] DEVELOPMENT OF OPTIMIZATION STRATEGIES IN THERMOSPRAY LIQUID-CHROMATOGRAPHY MASS-SPECTROMETRY [J].