ANTIFUNGAL ACTIVITY OF HALOPHENOLS AND HALONITROPHENOLS

被引：9

作者：

GERSHON, H ^{[1
]}

CLARKE, DD ^{[1
]}

GERSHON, M ^{[1
]}

机构：

[1] NEW YORK BOT GARDEN,BRONX,NY 10458

来源：

MONATSHEFTE FUR CHEMIE | 1995年 / 126卷 / 10期

关键词：

ANTIFUNGAL ACTIVITY; HALOPHENOLS; HALONITROPHENOLS;

D O I：

10.1007/BF00811385

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Thirty one compounds (phenol; its 12 possible monohalo analogues; 18 nitrophenols (2- and 4-nitrophenols, 4-, 5-, and 6-halo-2-nitrophenols, 3-halo-4-nitrophenols)) were tested for antifungal activity against six fungi (A. niger, A. oryzae, M. verrucaria, T. viride, M. cirinelloides, and T. mentayrophytes) in Sabouraud dextrose broth. The two most fungitoxic compounds of those studied were 5-fluoro- and 5-iodo-2-nitrophenols which inhibited all the fungi at concentrations under 10 mu g/ml. 6-Iodo-2-nitrophenol inhibited five fungi at a concentration below 10 mu g/ml and M. cirinelloides at 10-100 mu g/ml.

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页码：1161 / 1166

页数：6

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