INTRAVENOUS MAGNESIUM-SULFATE IN ACUTE, LIFE-THREATENING ASTHMA

被引:28
作者
KUITERT, LM [1 ]
KLETCHKO, SL [1 ]
机构
[1] MIDDLEMORE HOSP,EMERGENCY MED UNIT,AUCKLAND 6,NEW ZEALAND
关键词
magnesium sulfate; asthma;
D O I
10.1016/S0196-0644(05)81481-7
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Magnesium, a physiologic calcium antagonist, is known to have a direct effect on calcium uptake in smooth muscle, resulting in smooth muscle relaxation. Studies of magnesium sulfate infusions in patients with mild or moderate-to-severe acute asthma have shown that it may have a significant bronchodilatory effect, similar to that of salbutamol (albuterol). We present the case of a patient with acute severe life-threatening asthma (initially in cardiorespiratory arrest) who responded to an IV infusion of magnesium sulfate after aggressive pharmacologic management failed to result in clinical improvement.
引用
收藏
页码:1243 / 1245
页数:3
相关论文
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