CONTROLLED RELEASE OF INSULIN FROM POLYMER MATRICES - CONTROL OF DIABETES IN RATS

被引：78

作者：

BROWN, L

MUNOZ, C

SIEMER, L

EDELMAN, E

LANGER, R

机构：

[1] MIT, DEPT APPL BIOL SCI, CAMBRIDGE, MA 02139 USA

[2] MIT, WHITAKER COLL HLTH SCI TECHNOL & MANAGEMENT, CAMBRIDGE, MA 02139 USA

[3] MOLECULON BIOTECH, CAMBRIDGE, MA USA

[4] CHILDRENS HOSP MED CTR, DEPT SURG, BOSTON, MA 02115 USA

[5] HARVARD UNIV, SCH MED, BOSTON, MA 02115 USA

来源：

DIABETES | 1986年 / 35卷 / 06期

关键词：

D O I：

10.2337/diabetes.35.6.692

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：692 / 697

页数：6

共 15 条

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[2]

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[4]

BUCHWALD H, 1981, LANCET, V1, P1233

[5] SINTERING TECHNIQUE FOR THE PREPARATION OF POLYMER MATRICES FOR THE CONTROLLED RELEASE OF MACROMOLECULES [J].

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LANGER, R .

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[6] ONE MONTH OF SUSTAINED-RELEASE OF INSULIN FROM A POLYMER IMPLANT [J].

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[7] INSULIN DELIVERY DEVICES [J].

FELIG, P ;

TAMBORLANE, WV .

ANNALS OF INTERNAL MEDICINE, 1980, 93 (04) :627-629

[8] LONG-ACTING INSULIN - SLOW RELEASE OF INSULIN FROM A BIODEGRADABLE MATRIX IMPLANTED IN DIABETIC RATS [J].

GOOSEN, MFA ;

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OSHEA, GM ;

CHOU, S ;

SUN, AM .

DIABETES, 1983, 32 (05) :478-481

[9] ZERO-ORDER CONTROLLED-RELEASE POLYMER MATRICES FOR MICROMOLECULES AND MACROMOLECULES [J].

HSIEH, DST ;

RHINE, WD ;

LANGER, R .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1983, 72 (01) :17-22

[10]

IRSIGLER K, 1981, DIABETES, V19, P1

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