COMBINATORIAL CHEMISTRY - DIRECT ANALYSIS OF BEAD SURFACE-ASSOCIATED MATERIALS

被引:30
作者
HASKINS, NJ
HUNTER, DJ
ORGAN, AJ
RAHMAN, SS
THOM, C
机构
[1] SMITHKLINE BEECHAM PHARMACEUT,MED CHEM,HARLOW CM19 5AW,ESSEX,ENGLAND
[2] SMITHKLINE BEECHAM PHARMACEUT,ANALYT SCI,WELWYN GARDEN CIT AL6 9AR,HERTS,ENGLAND
关键词
D O I
10.1002/rcm.1290091421
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry has been used to analyse the results of solid-phase combinatorial chemistry on a single bead, A single component from a five-membered combinatorial library was positively identified using the method outlined in this paper.
引用
收藏
页码:1437 / 1440
页数:4
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