HISTAMINE CONTAINING ENDOCRINE-CELLS IN THE HUMAN STOMACH

被引：56

作者：

LONROTH, H

HAKANSON, R

LUNDELL, L

SUNDLER, F

机构：

[1] UNIV LUND, DEPT PHARMACOL, S-22101 LUND, SWEDEN

[2] UNIV LUND, DEPT MED CELL RES, S-22101 LUND, SWEDEN

来源：

GUT | 1990年 / 31卷 / 04期

关键词：

D O I：

10.1136/gut.31.4.383

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Histamine and chromogranin A-immunoreactive cells were studied in the mucosa of the human stomach. Cells reacting to both histamine and chromogranin A-antibodies (histamine containing endocrine cells), were demonstrated by double immunostaining and found to be restricted to the oxyntic mucosa. Histamine containing cells that did not stain with chromogranin A-antibodies were numerous throughout the stomach. Of the histamine immunoreactive cells in the oxyntic gland area 22% reacted with antibodies against chromogranin A. Histamine containing endocrine cells constituted 44% of the total number of endocrine cells in the oxyntic mucosa. These findings suggest that the histamine containing endocrine cells in the human stomach are identical with the so called enterochromaffin like cells.

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页码：383 / 388

页数：6

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