PATHOGENESIS OF ACANTHAMOEBIC KERATITIS - HYPOTHESIS BASED ON A HISTOLOGICAL ANALYSIS OF 30 CASES

被引：54

作者：

GARNER, A

机构：

[1] Department of Pathology, Institute of Ophthalmology, University of London, London EC1V 9EL, Bath Street

来源：

BRITISH JOURNAL OF OPHTHALMOLOGY | 1993年 / 77卷 / 06期

关键词：

D O I：

10.1136/bjo.77.6.366

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The results of a histopathological study of 30 cases of Acanthamoeba keratitis are construed as indicating a four stage pathogenetic sequence: (1) initial infection, involving breaching of the surface epithelium; (2) keratocyte depletion by the invading trophozoites; (3) inflammatory response mediated by neutrophil polymorphonuclear leucocytes; (4) stromal necrosis attributable to leucocytic activity.

引用

页码：366 / 370

页数：5

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