Mycotoxins, general view, chemistry and structure

被引:153
作者
Steyn, PS
机构
[1] SASOL Centre for Chemistry, Potchefstroom University, Potchefstroom
关键词
mycotoxin; aflatoxin; mycotoxicosis; hepatocarcinogen;
D O I
10.1016/0378-4274(95)03525-7
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 [卫生毒理学];
摘要
Mycotoxins induce diverse and powerful biological effects in test systems; some are carcinogenic, mutagenic, teratogenic, estrogenic, hemorrhagic, immunotoxic, nephrotoxic, hepatotoxic, dermotoxic, and neurotoxic. Mycotoxins have been unambiguously linked to the etiology of several diseases in animals. The discovery of aflatoxins in the early 1960s led to the resurgence of interest in human mycotoxicoses; mycotoxins are now recognized as causal cancer. ergotism and alimentary toxic aleukia. The fumonisins and ochratoxins are suspected of playing a role in the etiology of esophageal cancer and Balkan endemic nephrotoxicity, respectively.
引用
收藏
页码:843 / 851
页数:9
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