THE ANTIOXIDANT SYSTEM OF THE ORGANISM - THEORETICAL BASIS AND PRACTICAL CONSEQUENCES

被引:23
作者
LEWIN, G [1 ]
POPOV, I [1 ]
机构
[1] HUMBOLDT UNIV BERLIN,MED FAC CHARITE,ANTIOXIDANT THERAPY RES LAB,D-10117 BERLIN,GERMANY
关键词
D O I
10.1016/0306-9877(94)90130-9
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
On the basis of the literature and our own investigations, the antioxidant mechanisms and substances of the human organism are described and classified as compartmentalization, detoxification, repair and utilization. The existence and the structure of an antioxidant system, which serves as support of the antioxidant homeostasis, are hypothesized. A parameter for characterizing the state of the antioxidant system and for detecting its changes under pathological conditions - the integral antioxidant capacity of blood plasma - and a method for its determination are suggested.
引用
收藏
页码:269 / 275
页数:7
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共 61 条
  • [1] AKAZAWA N, 1986, J NUTR SCI VITAMINOL, V32, P41, DOI 10.3177/jnsv.32.41
  • [2] UBER EINE BIOLOGISCHE BEDEUTUNG DER GALLENFARBSTOFFE BILIRUBIN UND BILIVERDIN ALS ANTIOXYDANTIEN FUR DAS VITAMIN-A UND DIE ESSENTIELLEN FETTSAUREN
    BERNHARD, K
    RITZEL, G
    STEINER, KU
    [J]. HELVETICA CHIMICA ACTA, 1954, 37 (01) : 306 - 313
  • [3] BUHRING M, 1993, IN PRESS PHYS CHEM B
  • [4] ANNOTATION - ACTIVATED OXYGEN AND HEMOLYSIS
    CARRELL, RW
    WINTERBOURN, CC
    RACHMILEWITZ, EA
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1975, 30 (03) : 259 - 264
  • [5] CLEMENT I, 1984, LIFE SCI, V34, P2501
  • [6] VITAMIN-E AND RED BLOOD-CELL GLUTATHIONE
    COSTAGLIOLA, C
    LIBONDI, T
    MENZIONE, M
    RINALDI, E
    AURICCHIO, G
    [J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 1985, 34 (08): : 712 - 714
  • [7] DAM H, 1957, PHARMACOL REV, V9, P1
  • [8] DAVIES K J A, 1986, Journal of Free Radicals in Biology and Medicine, V2, P155, DOI 10.1016/S0748-5514(86)80066-6
  • [9] INDUCIBLE REPAIR OF OXIDATIVE DNA DAMAGE IN ESCHERICHIA-COLI
    DEMPLE, B
    HALBROOK, J
    [J]. NATURE, 1983, 304 (5925) : 466 - 468
  • [10] DEWAZIERS I, 1987, EXPERIENTIA, V43, P394, DOI 10.1007/BF01940423