SURAL NERVE BIOPSIES IN GUILLAIN-BARRE-SYNDROME - AXONAL DEGENERATION AND MACROPHAGE-ASSOCIATED DEMYELINATION AND ABSENCE OF CYTOMEGALOVIRUS GENOME

被引：59

作者：

HUGHES, R

ATKINSON, P

COATES, P

HALL, S

LEIBOWITZ, S

机构：

[1] UNITED MED & DENT SCH GUYS & ST THOMASS HOSP,DIV ANAT,LONDON SE1 9RT,ENGLAND

[2] ST BARTHOLOMEWS HOSP,DEPT HISTOPATHOL,LONDON EC1A 7BE,ENGLAND

来源：

MUSCLE & NERVE | 1992年 / 15卷 / 05期

关键词：

GUILLAIN-BARRE SYNDROME; NERVE BIOPSY; IMMUNOSTAINING; ELECTRON MICROSCOPY; CYTOMEGALOVIRUS;

D O I：

10.1002/mus.880150506

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

T-cell infiltration was detected by immunohistochemistry in only 2 of 10 sural nerve biopsies from patients with Guillain-Barre syndrome (GBS). The number of endoneurial macrophages, identified by the monoclonal antibody MAC 387. was increased, compared with the number in 10 cases of axonal neuropathy. Macrophage associated demyelination was identified in 7 and axonal degeneration in 8 cases. Cytomegalovirus (CMV) genome was not detected with the polymerase chain reaction.

引用

页码：568 / 575

页数：8

共 22 条

[1] SEQUENTIAL ELECTRODIAGNOSTIC ABNORMALITIES IN ACUTE INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY [J].