SYNTHESIS AND STEREOCHEMICAL STUDY OF CIS-1-(3'-SUBSTITUTED-PROPYL)BENZO[A]QUINOLIZIDINE AND TRANS-1-(3'-SUBSTITUTED-PROPYL)BENZO[A]QUINOLIZIDINE

被引：18

作者：

KOBOR, J

SOHAR, P

FULOP, F

机构：

[1] EOTVOS LORAND UNIV, DEPT GEN & INORGAN CHEM, H-1518 BUDAPEST 112, HUNGARY

[2] ALBERT SZENT GYORGYI MED UNIV, INST PHARMACEUT CHEM, H-6720 SZEGED, HUNGARY

来源：

TETRAHEDRON | 1994年 / 50卷 / 16期

关键词：

D O I：

10.1016/S0040-4020(01)85022-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

From 1-methyl-6,7-dimethoxy-3,4-dihydroisoquinoline with methyl or ethyl acrylate or with acrylonitrile, via Michael addition products, cis- and trans-1-(3'-substituted-propyl)benzo[a]quinolizidinones and quinolizidines were prepared. The relative configurations and the predominant conformations were determined by means of H-1 and C-13 NMR spectroscopy, with the application of DR, DNOE and 2D HSC measurements.

引用

页码：4873 / 4886

页数：14

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[3]

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