METABOLISM OF N-NITROSO-HYDROXYETHYL-ALKYLAMINE PHOSPHATE-ESTERS IN THE RAT

被引：7

作者：

FRANK, N

FREI, E

WIESSLER, M

机构：

来源：

TOXICOLOGY | 1989年 / 57卷 / 01期

关键词：

D O I：

10.1016/0300-483X(89)90034-6

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：59 / 67

页数：9

共 8 条

[1] SYNTHESIS OF C-14-LABELED NITROSAMINES .4. SYNTHESIS OF METHYL-(1-ACETOXY)METHYL-C-14 NITROSAMINE AND 1-C-14-ETHYL(ACETOXY)ETHYL NITROSAMINE [J].

BRAUN, H ;

WIESSLER, M .

JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1978, 14 (06) :887-892

[2] COMPUTATIONAL METHODS FOR THE SCREENING OF PHARMACOKINETIC PARAMETERS IN METABOLISM EXPERIMENTS [J].

EDLER, L ;

WAHRENDORF, J ;

FRANK, N .

INTERNATIONAL JOURNAL OF BIO-MEDICAL COMPUTING, 1983, 14 (05) :369-380

[3] N-NITROSO-HYDROXYALKYL-ALKYLAMINE PHOSPHATE-ESTERS - A NEW CLASS OF N-NITROSO COMPOUNDS [J].

FRANK, N ;

WIESSLER, M .

CARCINOGENESIS, 1986, 7 (03) :365-369

[4] ALKYLDIAZOHYDROXIDES ARE STABLE INTERMEDIATES IN THE DEGRADATION OF N-NITROSO-(ACETOXYALKYL)-ALKYLAMINES IN RAT SERUM [J].

FRANK, N ;

WIESSLER, M .

CARCINOGENESIS, 1983, 4 (06) :751-753

[5]

KNOX WE, 1976, ENZYME PATTERNS FETA, P292

[6] ISOLATION AND CHARACTERIZATION OF N-ALKYL-N-(HYDROXYMETHYL)NITROSAMINES FROM N-ALKYL-N-(HYDROPEROXYMETHYL)NITROSAMINES BY DEOXYGENATION [J].

MOCHIZUKI, M ;

ANJO, T ;

OKADA, M .

TETRAHEDRON LETTERS, 1980, 21 (38) :3693-3696

[7]

RUGEWITZBLACKHOLM B, 1987, LIEBIGS ANN CHEM, P583

[8]

WIESSLER M, 1984, IARC SCI PUBL, V57, P465

← 1 →