SYNTHESIS AND INVESTIGATION OF THE BETA-ADRENOCEPTOR AGONIST AND PLATELET ANTIAGGREGATORY PROPERTIES OF 1,7,8-TRISUBSTITUTED "2,3,4,5-TETRAHYDRO-1H-2-BENZAZEPINE ANALOGS OF TRIMETOQUINOL

被引：22

作者：

CLARK, MT

CHANG, J

NAVRAN, SS

HUZOORAKBAR

MUKHOPADHYAY, A

AMIN, H

FELLER, DR

MILLER, DD

机构：

[1] OHIO STATE UNIV, COLL PHARM, DIV MED CHEM, COLUMBUS, OH 43210 USA

[2] OHIO STATE UNIV, COLL PHARM, DIV PHARMACOGNOSY & PHARMACOL, COLUMBUS, OH 43210 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1986年 / 29卷 / 02期

关键词：

D O I：

10.1021/jm00152a003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：181 / 185

页数：5

共 32 条

[1] beta-piperonylpropionitrile and some derived substances. [J].

Baker, W ;

Robinson, R .

JOURNAL OF THE CHEMICAL SOCIETY, 1925, 127 :1424-1433

[2] 7-MEMBERED HETEROCYCLES .19. 1-ARALKYLATED TETRAHYDRO-2-BENZAZEPINES .2. SYNTHESIS FROM "3-(3,4-DIMETHOXYPHENYL)-PROPYLAMINE [J].

BERNEY, D ;

JAUNER, T .

HELVETICA CHIMICA ACTA, 1976, 59 (02) :623-626

[3]

BLIGH EG, 1959, CAN J BIOCHEM PHYS, V37, P911

[4] AGGREGATION OF BLOOD PLATELETS BY ADENOSINE DIPHOSPHATE AND ITS REVERSAL [J].

BORN, GVR .

NATURE, 1962, 194 (4832) :927-&

[5] PHOSPHOLIPID-METABOLISM IN STIMULATED HUMAN-PLATELETS - CHANGES IN PHOSPHATIDYLINOSITOL, PHOSPHATIDIC-ACID, AND LYSOPHOSPHOLIPIDS [J].

BROEKMAN, MJ ;

WARD, JW ;

MARCUS, AJ .

JOURNAL OF CLINICAL INVESTIGATION, 1980, 66 (02) :275-283

[6]

DECKER H, 1913, LIEBIGS ANN CHEM, P289

[7] COMPARATIVE ACTIONS OF TRIMETOQUINOL, TETRAHYDROPAPAVEROLINE AND SALSOLINOL ISOMERS IN BETA-ADRENOCEPTOR SYSTEMS [J].

FELLER, DR ;

VENKATRAMAN, R ;

MILLER, DD .

BIOCHEMICAL PHARMACOLOGY, 1975, 24 (13-1) :1357-1359

[8]

HAWORTH WN, 1907, J CHEM SOC, V91, P1087

[9] INVESTIGATION OF THE EFFECTS OF PHOSPHOLIPASE-C ON HUMAN-PLATELETS - EVIDENCE THAT AGGREGATION INDUCED BY PHOSPHOLIPASE-C IS INDEPENDENT OF PROSTAGLANDIN GENERATION, RELEASED ADP AND IS MODULATED BY CYCLIC-AMP [J].

HUZOORAKBAR ;

NAVRAN, SS ;

CHANG, J ;

MILLER, DD ;

FELLER, DR .

THROMBOSIS RESEARCH, 1982, 27 (04) :405-417

[10] ANTI-PLATELET ACTIONS OF TRIMETOQUINOL ISOMERS - EVIDENCE FOR INHIBITION OF A PROSTAGLANDIN-INDEPENDENT PATHWAY OF PLATELET-AGGREGATION [J].

HUZOORAKBAR ;

NAVRAN, SS ;

MILLER, DD ;

FELLER, DR .

BIOCHEMICAL PHARMACOLOGY, 1982, 31 (05) :886-889

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