EFFICIENT SYNTHESIS OF ENANTIOMERICALLY PURE 5,5-DIMETHYL-4-HYDROXY-2-CYCLOPENTENONE

被引：17

作者：

MIYAOKA, H ^{[1
]}

SAGAWA, S ^{[1
]}

NAGAOKA, H ^{[1
]}

YAMADA, Y ^{[1
]}

机构：

[1] TOKYO UNIV PHARM & LIFE SCI,HACHIOJI,TOKYO 19203,JAPAN

来源：

TETRAHEDRON-ASYMMETRY | 1995年 / 6卷 / 02期

关键词：

D O I：

10.1016/0957-4166(95)00042-N

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(+)- and (-)-5,5-Dimethyl-4-hydroxy-2-cyclopentenone 1 were efficiently synthesized by the dissymmetrization of meso diol 2 with lipase-catalyzed acetylation as a key step. The synthesis of (+)-5,5-dimethyl-4-hydroxy-2-cyclopentenone was also carried out by the chemical conversion of (-)-pantolactone 6.

引用

页码：587 / 594

页数：8

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