PHYSIOLOGICAL PULSATILE FLOW EXPERIMENTS IN A MODEL OF THE HUMAN AORTIC-ARCH

被引:51
作者
YEARWOOD, TL
CHANDRAN, KB
机构
[1] UNIV IOWA,COLL ENGN,CTR MAT RES,IOWA CITY,IA 52242
[2] UNIV IOWA,COLL ENGN,DIV MAT ENGN,HEMODYNAM LAB,IOWA CITY,IA 52242
关键词
BIOMEDICAL ENGINEERING - Physiological Models;
D O I
10.1016/0021-9290(82)90023-9
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The model aortic arch flow chamber was fabricated in clear acrylic from an in situ casting of the human aorta and was incorporated in a mock-circulatory system. The model excluded the coronary sinuses and the three major branching arteries of the mid-arch region in order to concentrate only upon the effects of the multi-dimensional curvatures and tapering in the aorta. Furthermore, a flow straightening section was palced upstream to the flow chamber to eliminate any fluid disturbances created by the prosthetic aortic valve used in these studied. The qualitative flow visualization studies in the model aorta revealed the presence of strong secondary fluid motions near the inner wall. These helical flows dissipated during diastole, being greatly affected by the dramatic flow reversals which occurred along the inner wall at the onset of diastole. Quantitative studies were conducted using a three-sensor hot-film velocity probe to determine the axial, radial and tangential velocity components at various cross-sections in the aorta. The results showed rapid reversal of axial velocity near the inner wall at the onset of diastole.
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页码:683 / &
相关论文
共 17 条
[1]   FLUID DYNAMIC ASPECTS OF ARTERIAL-DISEASE [J].
BERGEL, DH ;
NEREM, RM ;
SCHWARTZ, CJ .
ATHEROSCLEROSIS, 1976, 23 (02) :253-261
[2]   ATHEROMA AND ARTERIAL WALL SHEAR - OBSERVATION, CORRELATION AND PROPOSAL OF A SHEAR DEPENDENT MASS TRANSFER MECHANISM FOR ALTHEROGENESIS [J].
CARO, CG ;
FITZGERA.JM ;
SCHROTER, RC .
PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1971, 177 (1046) :109-+
[3]  
CARO CG, 1977, CARDIOVASCULAR FLOW, P473
[4]   EXPERIMENTAL-STUDY OF PHYSIOLOGICAL PULSATILE FLOW IN A CURVED TUBE [J].
CHANDRAN, KB ;
YEARWOOD, TL .
JOURNAL OF FLUID MECHANICS, 1981, 111 (OCT) :59-85
[5]   EXPERIMENTAL-STUDY OF PULSATILE FLOW IN A CURVED TUBE [J].
CHANDRAN, KB ;
YEARWOOD, TL ;
WIETING, DW .
JOURNAL OF BIOMECHANICS, 1979, 12 (10) :793-805
[6]  
CHOI VS, 1979, J FLUID MECH, V193, P229
[7]   FLOW IN THE THORACIC AORTA [J].
FARTHING, S ;
PERONNEAU, P .
CARDIOVASCULAR RESEARCH, 1979, 13 (11) :607-620
[10]  
ROACH M, 1977, CARDIOVASCUALR FLOW, pCH14