A DOUBLE-BLIND COMPARISON OF VENLAFAXINE AND FLUOXETINE IN PATIENTS HOSPITALIZED FOR MAJOR DEPRESSION AND MELANCHOLIA

被引：265

作者：

CLERC, GE

RUIMY, P

VERDEAUPAILLES, J

机构：

[1] Centre Hospitaller, Pontorson

来源：

INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY | 1994年 / 9卷 / 03期

关键词：

DEPRESSION; FLUOXETINE; HOSPITALIZED PATIENTS; MELANCHOLIA;

D O I：

10.1097/00004850-199409000-00001

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The antidepressant efficacy and short-term safety of venlafaxine and fluoxetine were compared in 68 patients hospitalized with major depression and melancholia. Venlafaxine was superior in efficacy to fluoxetine; total scores for both the MADRS and the HAM-D were significantly (p less than or equal to 0.05) lower in the venlafaxine group than in the fluoxetine group at Weeks 4 and 6. Overall tolerance was similar for the two treatments.

引用

页码：139 / 143

页数：5

共 15 条

[1] RAPID DOWN REGULATION OF BETA-ADRENOCEPTORS BY CO-ADMINISTRATION OF DESIPRAMINE AND FLUOXETINE [J].