STIMULATION OF SPISULA SPERM MOTILITY BY 5-HYDROXYTRYPTAMINE ANALOGS

被引：24

作者：

KADAM, AL

KOIDE, SS

机构：

[1] POPULAT COUNCIL,CTR BIOMED RES,1230 YORK AVE,NEW YORK,NY 10021

[2] MARINE BIOL LAB,WOODS HOLE,MA 02543

来源：

INVERTEBRATE REPRODUCTION & DEVELOPMENT | 1990年 / 17卷 / 01期

关键词：

Oxygen consumption; Serotonin; Sperm motility; Spisula gametes;

D O I：

10.1080/07924259.1990.9672085

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Serotonin (5-hydroxytryptamine, 5-HT) added to cold-immobilized Spisula sperm reinitiated motility. The response was instantaneous and dose-dependent at concentrations ranging from 1 to 5 µm. The 5-HT agonists, 8-OH-DPAT, 5-methoxytryptamine and 2-methyl-5-HT, were effective inducers while RU 24969 and 5-hydroxyindole-3-acetic acid were not. Paralleling the stimulation of sperm motility, 5-HT increased oxygen consumption of Spisula sperm, reflecting acceleration of respiration. Of the various species tested, 5-HT stimulated only Spisula sperm. © 1990 Balaban.

引用

页码：33 / 37

页数：5

共 18 条

[1]

DONATSCH P, 1984, British Journal of Pharmacology, V81, p34P

[2]

FORD WCL, 1981, J REPROD FERTIL, V63, P271

[3] MDL-72222 - A POTENT AND HIGHLY SELECTIVE ANTAGONIST AT NEURONAL 5-HYDROXYTRYPTAMINE RECEPTORS [J].