CYTOLOGIC EVIDENCE FOR GENE AMPLIFICATION IN METHOTREXATE-RESISTANT CELLS OBTAINED FROM A PATIENT WITH OVARIAN ADENOCARCINOMA

被引：108

作者：

TRENT, JM

BUICK, RN

OLSON, S

HORNS, RC

SCHIMKE, RT

机构：

[1] UNIV ARIZONA, CTR CANC, TUCSON, AZ 85724 USA

[2] ONTARIO CANC INST, DEPT MED BIOPHYS, TORONTO M4X 1K9, ONTARIO, CANADA

[3] STANFORD UNIV, DEPT BIOL, STANFORD, CA 94305 USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 1984年 / 2卷 / 01期

关键词：

D O I：

10.1200/JCO.1984.2.1.8

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：8 / 15

页数：8

共 31 条

[1]

ALT FW, 1978, J BIOL CHEM, V253, P1357

[2]

BERTINO JR, 1982, GENE AMPLIFICATION, P23

[3] METAPHASE CHROMOSOME ANOMALY - ASSOCIATION WITH DRUG-RESISTANCE AND CELL-SPECIFIC PRODUCTS [J].

BIEDLER, JL ;

SPENGLER, BA .

SCIENCE, 1976, 191 (4223) :185-187

[4]

BIEDLER JL, 1982, GENE AMPLIFICATION, P39

[5] RELATIONSHIP OF AMPLIFIED DIHYDROFOLATE-REDUCTASE GENES TO DOUBLE MINUTE CHROMOSOMES IN UNSTABLY RESISTANT MOUSE FIBROBLAST CELL-LINES [J].

BROWN, PC ;

BEVERLEY, SM ;

SCHIMKE, RT .

MOLECULAR AND CELLULAR BIOLOGY, 1981, 1 (12) :1077-1083

[6] EFFECT OF HOST-CELL INTERACTIONS ON CLONOGENIC CARCINOMA-CELLS IN HUMAN-MALIGNANT EFFUSIONS [J].

BUICK, RN ;

FRY, SE ;

SALMON, SE .

BRITISH JOURNAL OF CANCER, 1980, 41 (05) :695-704

[7] DISTINGUISHING CHARACTERISTICS OF A NEW NEURO-BLASTOMA CELL-LINE [J].

CASPER, JT ;

TRENT, JM ;

HARB, J ;

PIASKOWSKI, V ;

HELMSWORTH, M ;

FINLAN, J ;

VONHOFF, DD .

CANCER GENETICS AND CYTOGENETICS, 1983, 10 (02) :177-186

[8] UNSTABLE METHOTREXATE RESISTANCE IN HUMAN SMALL-CELL CARCINOMA ASSOCIATED WITH DOUBLE MINUTE CHROMOSOMES [J].

CURT, GA ;

CARNEY, DN ;

COWAN, KH ;

JOLIVET, J ;

BAILEY, BD ;

DRAKE, JC ;

KAOSHAN, CS ;

MINNA, JD ;

CHABNER, BA .

NEW ENGLAND JOURNAL OF MEDICINE, 1983, 308 (04) :199-202

[9] CORRELATION OF DIHYDROFOLATE-REDUCTASE ELEVATION WITH GENE AMPLIFICATION IN A HOMOGENEOUSLY STAINING CHROMOSOMAL REGION IN L5178Y CELLS [J].

DOLNICK, BJ ;

BERENSON, RJ ;

BERTINO, JR ;

KAUFMAN, RJ ;

NUNBERG, JH ;

SCHIMKE, RT .

JOURNAL OF CELL BIOLOGY, 1979, 83 (02) :394-402

[10] METHOTREXATE-RESISTANT CHINESE-HAMSTER OVARY CELLS CONTAIN A DIHYDROFOLATE-REDUCTASE WITH AN ALTERED AFFINITY FOR METHOTREXATE [J].

FLINTOFF, WF ;

ESSANI, K .

BIOCHEMISTRY, 1980, 19 (18) :4321-4327

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