THE THYROADRENAL AXIS, FOOD-DEPRIVATION AND RETENTION OF A BEHAVIORAL-RESPONSE

被引：5

作者：

JEFFERYS, DE ^{[1
]}

FUNDER, JW ^{[1
]}

机构：

[1] BAKER MED RES INST,POB 348,PRAHRAN,VIC 3181,AUSTRALIA

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY | 1993年 / 239卷 / 1-3期

关键词：

ADRENALECTOMY; IMMOBILITY; PORSOLT SWIMMING TEST; HYPOTHYROIDISM; FOOD DEPRIVATION;

D O I：

10.1016/0014-2999(93)90993-R

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The effects of adrenalectomy on retention of the immobile response in the Porsolt swimming rat test are equally reversed by dexamethasone, ketocyclazocine and thyroxine; the effects of hypothyroidism are similarly equally well reversed by all three agents, or by adrenalectomy. Animals food deprived for 24 h lose the response, but retain it after 48 h food deprivation; the latter effect is blocked by adrenalectomy. These counterintuitive findings suggest hitherto unrecognized commonalities and/or interactions in the metabolic effects of the thyroid and adrenal glands.

引用

页码：189 / 193

页数：5

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