ACTIVE-SITE DIRECTED N-CARBOXYMETHYL PEPTIDE INHIBITORS OF A SOLUBLE METALLOENDOPEPTIDASE FROM RAT-BRAIN

被引：86

作者：

CHU, TG ^{[1
]}

ORLOWSKI, M ^{[1
]}

机构：

[1] CUNY MT SINAI SCH MED,DEPT PHARMACOL,NEW YORK,NY 10029

来源：

BIOCHEMISTRY | 1984年 / 23卷 / 16期

关键词：

D O I：

10.1021/bi00311a005

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：3598 / 3603

页数：6

共 25 条

[1] MEMBRANE-BOUND KIDNEY NEUTRAL METALLOENDOPEPTIDASE - INTERACTION WITH SYNTHETIC SUBSTRATES, NATURAL PEPTIDES, AND INHIBITORS [J].

ALMENOFF, J ;

ORLOWSKI, M .

BIOCHEMISTRY, 1983, 22 (03) :590-599

[2] MEMBRANE-BOUND PITUITARY METALLOENDOPEPTIDASE - APPARENT IDENTITY TO ENKEPHALINASE [J].

ALMENOFF, J ;

WILK, S ;

ORLOWSKI, M .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 102 (01) :206-214

[3]

Bratton AC, 1939, J BIOL CHEM, V128, P537

[4] DESIGN OF POTENT COMPETITIVE INHIBITORS OF ANGIOTENSIN-CONVERTING ENZYME - CARBOXYALKANOYL AND MERCAPTOALKANOYL AMINO-ACIDS [J].

CUSHMAN, DW ;

CHEUNG, HS ;

SABO, EF ;

ONDETTI, MA .

BIOCHEMISTRY, 1977, 16 (25) :5484-5491

[5] THE DETERMINATION OF ENZYME INHIBITOR CONSTANTS [J].

DIXON, M .

BIOCHEMICAL JOURNAL, 1953, 55 (01) :170-171

[6] DIFFERENTIAL RECOGNITION OF ENKEPHALINASE AND ANGIOTENSIN-CONVERTING ENZYME BY NEW CARBOXYALKYL INHIBITORS [J].

FOURNIEZALUSKI, MC ;

SOROCALUCAS, E ;

WAKSMAN, G ;

LLORENS, C ;

SCHWARTZ, JC ;

ROQUES, BP .

LIFE SCIENCES, 1982, 31 (26) :2947-2954

[7]

GOLDBARG JA, 1958, CANCER, V11, P283, DOI 10.1002/1097-0142(195803/04)11:2<283::AID-CNCR2820110209>3.0.CO

[8]

2-8

[9]

Hartsuck J. A., 1971, ENZYMES, V3, P1

[10] METAL-COORDINATING SUBSTRATE-ANALOGS AS INHIBITORS OF METALLOENZYMES [J].

HOLMQUIST, B ;

VALLEE, BL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (12) :6216-6220

← 1 2 3 →