EXACERBATION OF ULCERATIVE-COLITIS DURING ALPHA-INTERFERON THERAPY FOR CHRONIC HEPATITIS-C

被引：37

作者：

MITORO, A

YOSHIKAWA, M

YAMAMOTO, K

MIMURA, M

YOSHIKAWA, Y

SHIROI, A

MOCHI, T

SAKAMOTO, T

YAMAO, J

KIKUCHI, E

FUKUI, H

TSUJII, T

机构：

[1] Department of Gastroenterology, Hattori Memorial Hospital, Kitakatsuragi-gun Nara

[2] Third Department of Internal Medicine, Nara Medical University, Kashihara Nara

来源：

INTERNAL MEDICINE | 1993年 / 32卷 / 04期

关键词：

SULFASALAZINE; AUTOIMMUNE DISORDERS;

D O I：

10.2169/internalmedicine.32.327

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a 34-year-old man with chronic hepatitis C who showed exacerbation of ulcerative colitis during alpha-interferon (IFNalpha) therapy. Discontinuance of the IFNalpha therapy improved his symptoms, suggesting that IFNalpha administration might worsen ulcerative colitis. The administration of sulfasalazine allowed the patient to receive IFNalpha again without flare-up of ulcerative colitis. This case suggests the possible efficacy of sulfasalazine therapy in patients with ulcerative colitis complicated by some other diseases requiring IFNalpha administration.

引用

页码：327 / 331

页数：5

共 24 条

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