SNAIL AND SPIDER TOXINS SHARE A SIMILAR TERTIARY STRUCTURE AND CYSTINE MOTIF

被引：89

作者：

NARASIMHAN, L ^{[1
]}

SINGH, J ^{[1
]}

HUMBLET, C ^{[1
]}

GURUPRASAD, K ^{[1
]}

BLUNDELL, T ^{[1
]}

机构：

[1] UNIV LONDON BIRKBECK COLL,LONDON WC1E 7HX,ENGLAND

来源：

NATURE STRUCTURAL BIOLOGY | 1994年 / 1卷 / 12期

关键词：

D O I：

10.1038/nsb1294-850

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The similar tertiary folds of toxins from two diverse biological sources indicates a functional relevance for this common motif.

引用

页码：850 / 852

页数：3

共 16 条

[1] TOXITYPING RAT-BRAIN CALCIUM CHANNELS WITH OMEGA-TOXINS FROM SPIDER AND CONE SNAIL VENOMS [J].

ADAMS, ME ;

MYERS, RA ;

IMPERIAL, JS ;

OLIVERA, BM .

BIOCHEMISTRY, 1993, 32 (47) :12566-12570

[2]

ADAMS ME, 1993, MOL PHARMACOL, V44, P681

[3] PROTEIN DATA BANK - COMPUTER-BASED ARCHIVAL FILE FOR MACROMOLECULAR STRUCTURES [J].

BERNSTEIN, FC ;

KOETZLE, TF ;

WILLIAMS, GJB ;

MEYER, EF ;

BRICE, MD ;

RODGERS, JR ;

KENNARD, O ;

SHIMANOUCHI, T ;

TASUMI, M .

JOURNAL OF MOLECULAR BIOLOGY, 1977, 112 (03) :535-542

[4] SOLUTION STRUCTURE OF OMEGA-CONOTOXIN GVIA USING 2-D NMR-SPECTROSCOPY AND RELAXATION MATRIX ANALYSIS [J].

DAVIS, JH ;

BRADLEY, EK ;

MILJANICH, GP ;

NADASDI, L ;

RAMACHANDRAN, J ;

BASUS, VJ .

BIOCHEMISTRY, 1993, 32 (29) :7396-7405

[5] MOLSCRIPT - A PROGRAM TO PRODUCE BOTH DETAILED AND SCHEMATIC PLOTS OF PROTEIN STRUCTURES [J].

KRAULIS, PJ .

JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1991, 24 :946-950

[6] OMEGA-CONOTOXIN - DIRECT AND PERSISTENT BLOCKADE OF SPECIFIC TYPES OF CALCIUM CHANNELS IN NEURONS BUT NOT MUSCLE [J].

MCCLESKEY, EW ;

FOX, AP ;

FELDMAN, DH ;

CRUZ, LJ ;

OLIVERA, BM ;

TSIEN, RW ;

YOSHIKAMI, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (12) :4327-4331

[7]

MENEZ A, 1992, P ROY SOC EDINB, V998, P83

[8] CONUS PEPTIDES AS CHEMICAL PROBES FOR RECEPTORS AND ION CHANNELS [J].

MYERS, RA ;

CRUZ, LJ ;

RIVIER, JE ;

OLIVERA, BM .

CHEMICAL REVIEWS, 1993, 93 (05) :1923-1936

[9] SYNTHESIS OF OMEGA-AGATOXIN IVA AND ITS RELATED PEPTIDES [J].

NISHIO, H ;

KUMAGAYE, KY ;

KUBO, S ;

CHEN, YN ;

MOMIYAMA, A ;

TAKAHASHI, T ;

KIMURA, T ;

SAKAKIBARA, S .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993, 196 (03) :1447-1453

[10]

NISHIUCHI Y, 1986, BIOPOLYMERS, V25, pS61

← 1 2 →