A SIMPLE SYNTHESIS OF PSI((E)CH=CH)GLY DIPEPTIDE ISOSTERES VIA REDUCTIVE ELIMINATION OF GAMMA-OXYGENATED ALPHA,BETA-ENOATES WITH ALKENYLCOPPER REAGENTS

被引：31

作者：

FUJII, N ^{[1
]}

HABASHITA, H ^{[1
]}

SHIGEMORI, N ^{[1
]}

OTAKA, A ^{[1
]}

IBUKA, T ^{[1
]}

TANAKA, M ^{[1
]}

YAMAMOTO, Y ^{[1
]}

机构：

[1] TOHOKU UNIV,FAC SCI,DEPT CHEM,SENDAI,MIYAGI 980,JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 37期

关键词：

DIPEPTIDE ISOSTERES; PSI((E)CH=CH)GLY; GAMMA-MESYLOXY-ALPHA; BETA-ENOATES; ALKENYLCOPPER REAGENTS; REDUCTIVE ELIMINATION;

D O I：

10.1016/S0040-4039(00)93510-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Readily available protected forms of delta-amino-gamma-mesyloxy-alpha,beta-enoates can be converted to protected dipeptide isosteres, PSI[(E)CH = CH]Gly, in high yields by reduction with alkenylcopper reagents.

引用

页码：4969 / 4972

页数：4

共 24 条

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