SYNTHESIS AND ANTI-TUMOR ACTIVITY OF 10-ALKYL-10-DEAZAMINOPTERINS - A CONVENIENT SYNTHESIS OF 10-DEAZAMINOPTERIN

被引：64

作者：

DEGRAW, JI

BROWN, VH

TAGAWA, H

KISLIUK, RL

GAUMONT, Y

SIROTNAK, FM

机构：

[1] TUFTS UNIV,SCH MED,DEPT BIOCHEM,BOSTON,MA 02111

[2] MEM SLOAN KETTERING CANC CTR,DEPT EXPTL THERAPEUT,NEW YORK,NY 10021

来源：

关键词：

D O I：

10.1021/jm00352a026

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1227 / 1230

页数：4

共 14 条

[1] PTERIDINES .3. UNAMBIGUOUS SYNTHESES OF XANTHOPTERIN AND 2-AMINO-4-HYDROXY-6-METHYLPTERIDINE
BOON, WR
LEIGH, T
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1951, (JUN): : 1497 - 1501
[2] Creger P. L., 1970, J AM CHEM SOC, V92, P1396, DOI DOI 10.1021/JA00708A048
[3] SYNTHESIS AND ANTIFOLATE ACTIVITY OF 10-DEAZAMINOPTERIN
DEGRAW, JI
KISLIUK, RL
GAUMONT, Y
BAUGH, CM
NAIR, MG
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (05) : 552 - 553
[4] 2,4-DIAMINO-6-ARYLETHYLPTERIDINES AS STREPTOCOCCUS-FAECIUM GROWTH INHIBITORS
DEGRAW, JI
BROWN, VH
KISLIUK, RL
GAUMONT, Y
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (09) : 866 - &
[5] DEGRAW JI, 1979, CHEM BIOL PTERIDINES, P225
[6] HOFF S, 1969, RECL TRAV CHIM PAY-B, V88, P845
[7] CONVENIENT SYNTHESIS OF 10-DEAZAAMINOPTERIN VIA A PTERIDINE YLIDE
PIPER, JR
MONTGOMERY, JA
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1980, 23 (03) : 320 - 321
[8] SIROTNAK FM, 1978, CANCER TREAT REP, V62, P1047
[9] CORRELATES OF FOLATE ANALOG TRANSPORT, PHARMACOKINETICS AND SELECTIVE ANTI-TUMOR ACTION
SIROTNAK, FM
[J]. PHARMACOLOGY & THERAPEUTICS, 1980, 8 (01) : 71 - 103
[10] SIROTNAK FM, 1977, P AM ASSOC CANC RES, V18, P37